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Imaging Biological Samples with Optical Microscopy01:18

Imaging Biological Samples with Optical Microscopy

Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...

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Moving beyond the desktop: prospects for practical bioimage analysis via the web.

Wei Ouyang1, Kevin W Eliceiri2, Beth A Cimini3

  • 1Science for Life Laboratory, Department of Applied Physics, KTH Royal Institute of Technology, Stockholm, Sweden.

Frontiers in Bioinformatics
|August 10, 2023
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Summary

Transitioning bioimage analysis to web-based platforms enhances accessibility and collaboration. This shift addresses computational demands and reproducibility challenges in biological imaging research.

Keywords:
bioimage analysisbrowser computingcloud computingcollaboration in sciencedata accessibility and reusabilitydata managementweb-based tools

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Area of Science:

  • Life Sciences
  • Bioimaging
  • Computational Biology

Background:

  • Advancements in biological imaging generate complex data, challenging traditional desktop-based analysis methods.
  • Current bioimage analysis tools face issues with accessibility, installation, and reproducibility.

Purpose of the Study:

  • To advocate for a transition from desktop to web-based bioimage analysis.
  • To highlight the benefits of web-based tools for accessibility, collaboration, and workflow efficiency.
  • To explore the current landscape, challenges, and community involvement in web-based bioimage analysis.

Main Methods:

  • Perspective-based analysis of current bioimage analysis trends.
  • Discussion of potential benefits and challenges of web-based platforms.
  • Exploration of implementation strategies, including prototyping and workflow application.

Main Results:

  • Web-based bioimage analysis offers reduced local computational needs and overcomes installation barriers.
  • It provides solutions for enhanced reproducibility and streamlined scientific workflows.
  • A combined approach of prototyping and large-scale application is suggested for optimal implementation.

Conclusions:

  • Web-based bioimage analysis democratizes scientific research by improving accessibility and collaboration.
  • This transition can accelerate biological discovery through efficient and robust platforms.
  • Collective scientific community involvement is crucial for successful adoption.