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Cyberbiosecurity in high-containment laboratories.

Elizabeth Crawford1, Adam Bobrow2, Landy Sun1

  • 1Gryphon Scientific, Takoma Park, MD, United States.

Frontiers in Bioengineering and Biotechnology
|August 10, 2023
PubMed
Summary
This summary is machine-generated.

High-containment laboratories (HCLs) face unique cybersecurity risks due to their critical research on dangerous pathogens. This study introduces a novel asset-impact analysis to identify and mitigate these cyberbiosecurity threats, enhancing laboratory safety and security.

Keywords:
biosafetybiosecuritycyberbiosecuritycybersecurityhigh-containment laboratories (HCLs)risk assessment

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Area of Science:

  • Cyberbiosecurity
  • Laboratory Cybersecurity
  • Risk Management

Background:

  • High-containment laboratories (HCLs) are crucial for researching dangerous pathogens and producing vaccines.
  • Modern HCLs increasingly rely on cyber-connected infrastructure, introducing unique cybersecurity and cyberphysical risks.
  • Cyberbiosecurity, the intersection of cybersecurity and biological risks, is an emerging field with limited established risk assessment approaches.

Purpose of the Study:

  • To present a novel approach for cybersecurity risk assessment and mitigation in HCLs.
  • To identify common cyber and cyberphysical systems and workflows within HCLs.
  • To analyze potential adverse outcomes from cyber system compromises in HCLs.

Main Methods:

  • Conducted an asset-impact analysis tailored to the HCL environment.
  • Identified common cyber and cyberphysical systems and summarized typical cyber-workflows.
  • Categorized potential consequences of cyber system compromise (scientific advancement, public health, safety, security, financial impact).

Main Results:

  • A framework for identifying HCL-specific cyber assets and their potential impacts was developed.
  • Potential consequences of cyber compromises were broadly categorized.
  • Risk mitigation strategies, referencing CIS Controls, were discussed for HCLs.

Conclusions:

  • The study provides a novel approach to evaluating cyberbiosecurity risks in HCLs.
  • Awareness among HCL decision-makers regarding cyber risks to safety and security is raised.
  • The approach aids in identifying cyber-connected assets and impacts, guiding risk mitigation efforts.