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Determining patient value profiles in psoriasis
N T Hilhorst1,2, E Abatih3, E Deprez1,2
1Dermatology Research Unit, Ghent University, Ghent, Belgium.
Experimental Dermatology
|August 11, 2023
Summary
This study identified three distinct patient value profiles for psoriasis patients, enabling healthcare professionals to tailor treatments for better outcomes and value. These profiles help guide psoriasis management for a more goal-oriented approach.
Area of Science:
- Dermatology
- Health Economics
- Patient-Reported Outcomes
Background:
- Healthcare professionals (HCPs) aim to maximize patient value, defined as health outcomes relative to costs.
- Identifying individual patient-relevant outcomes in psoriasis remains a challenge.
Purpose of the Study:
- To define distinct 'patient value profiles' within a psoriasis cohort.
- To enable translation of these profiles into daily practice for enhanced individual patient value.
Main Methods:
- Hierarchical clustering on principal components (HCPC) was used to group patients with similar outcome rankings.
- A multi-class decision tree (MDT) was developed to assign patients to identified clusters using socio-demographic and clinical data.
Main Results:
- 120 psoriasis patients participated; median age 50, 36.7% female, median PASI 2.4, median disease duration 17 years.
- Three distinct patient value profiles were identified: Quality of Life (QoL), cost, and treatment.
- The developed MDT achieved a 64% accuracy in assigning patients to these profiles.
Conclusions:
- Three distinct patient value profiles were identified in the psoriasis cohort.
- A MDT facilitates easy patient assignment to these profiles.
- HCPs can utilize these profiles to personalize psoriasis management for a more goal-directed approach.
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