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Validated Tools for Screening Sarcopenia: A Scoping Review.

Rongna Lian1, Gengchen Jiang2, Qianqian Liu2

  • 1National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, China; Center of Gerontology and Geriatrics, West China Hospital, Sichuan University, Chengdu, China.

Journal of the American Medical Directors Association
|August 11, 2023
PubMed
Summary

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Blood biomarkers for sarcopenia: A systematic review and meta-analysis of diagnostic test accuracy studies.

Ageing research reviews·2023

This review summarizes over 50 validated sarcopenia screening tools, aiding clinicians in selecting optimal methods for diverse clinical settings and guiding future tool development.

Area of Science:

  • Gerontology
  • Clinical Diagnostics
  • Public Health

Background:

  • Sarcopenia screening tool selection is complex.
  • Validated tools are crucial for early detection and intervention.
  • A comprehensive overview of available tools is needed.

Purpose of the Study:

  • To systematically review and summarize all validated sarcopenia screening tools.
  • To assess the diagnostic accuracy of these tools across various populations.
  • To provide a resource for selecting appropriate tools in different clinical scenarios.

Main Methods:

  • Conducted a scoping review of 3 major databases (MEDLINE, EMBASE, CENTRAL) in April 2022.
  • Included 102 diagnostic accuracy studies involving 53 unique sarcopenia screening tools.
Keywords:
Muscle wastingbiomarkersevidence mappingmuscle depletionquestionnaires

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  • Extracted and summarized tool content, characteristics, and citation counts.
  • Main Results:

    • Identified 53 screening tools categorized into 7 groups (questionnaires, biomarkers, physical tests, etc.).
    • Highlighted frequently used tools like SARC-F, handgrip strength tests, and calf circumference measurements.
    • Noted significant variation in tool content and assessed domains, including physical function, biomarkers, and lifestyle factors.

    Conclusions:

    • Over 50 validated sarcopenia screening tools exist for diverse clinical settings.
    • This review assists clinicians and researchers in choosing optimal tools for specific scenarios.
    • Findings can inform the development of novel and improved sarcopenia screening instruments.