Patients Undergoing Systemic Anti-Cancer Therapy Who Require Surgical Intervention: What Surgeons Need to Know
Matthew D Robinson1, Mairéad G McNamara1,2, Hamish W Clouston1,3
1Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology Medicine and Health, The University of Manchester, Manchester M13 9NT, UK.
Cancers
|August 12, 2023
Summary
Systemic anti-cancer therapy (SACT) can increase surgical risks for cancer patients. This review highlights precautions for surgical teams managing patients on SACT.
Area of Science:
- Oncology
- Surgical Oncology
- Pharmacology
Background:
- Cancer patients often receive systemic anti-cancer therapy (SACT) for cure or palliation.
- SACT encompasses chemotherapy, targeted therapies, immunotherapy, and more.
- Surgical interventions may be required during SACT for urgent or emergency reasons.
Purpose of the Study:
- To review the evidence on surgical risks associated with SACT.
- To outline precautions for surgical teams managing patients undergoing SACT.
Main Methods:
- Narrative review of existing literature.
- Examination of SACT-associated surgical risks and management strategies.
Main Results:
- SACT can significantly impact surgical outcomes and patient safety.
- Specific SACT agents present unique perioperative considerations.
- Proactive management and multidisciplinary collaboration are crucial.
Conclusions:
- Understanding SACT-associated surgical risks is vital for optimal patient care.
- Implementing specific precautions can mitigate perioperative complications.
- Further research is needed to refine management guidelines.
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