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Updated: Jul 19, 2025
06:50
Extraction and Analysis of Taiwanese Green Propolis
Published on: January 7, 2019
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Radioprotective Effects from Propolis: A Review.
Blanca Ibáñez1, Ana Melero2, Alegría Montoro3,4
1Food & Health Laboratory, Institute of Materials Science, University of Valencia, 46980 Paterna, Spain.
Molecules (Basel, Switzerland)
|August 12, 2023
Summary
Propolis, a natural bee resin, demonstrates radioprotective effects. This review of 27 studies across cell, animal, and human models highlights its potential in radiation protection, particularly ethanolic extracts (EEP).
Area of Science:
- Natural Products Chemistry
- Radioprotection Research
- Pharmacology
Background:
- Propolis, a resinous substance from bees, possesses known antimicrobial, anti-inflammatory, and wound-healing properties.
- Its use spans centuries, attributed to diverse plant-derived components.
- Understanding its radioprotective potential is an emerging area of scientific interest.
Purpose of the Study:
- To systematically review and synthesize the existing literature on the radioprotective effects of propolis.
- To evaluate evidence from cell-based studies, animal models, and human trials.
- To identify key propolis characteristics and formulations associated with radioprotective efficacy.
Main Methods:
- A comprehensive literature search was conducted using PubMed and Embase databases.
- The review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.
- Twenty-seven relevant articles were selected, encompassing cell-based (n=8), animal (n=14), and human (n=5) studies.
Main Results:
- Propolis exhibits radioprotective properties, supported by evidence from various study types.
- Commonly studied forms include ethanolic extracts of propolis (EEP), water-soluble derivatives, and capsules.
- EEP, particularly from specific geographical origins (Brazil, Croatia, Egypt, Europe, Spain), showed significant lipophilic bioactive compounds like flavones, flavonols, and flavanones.
Conclusions:
- Propolis, especially EEP, demonstrates significant potential as a radioprotective agent.
- The efficacy is linked to its complex composition, including flavanones, flavones, and flavonols.
- Further research is warranted to fully characterize and optimize propolis-based radioprotective strategies, addressing batch variability.
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