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Updated: Jul 19, 2025

Enzymatic Synthesis of Epoxidized Metabolites of Docosahexaenoic, Eicosapentaenoic, and Arachidonic Acids
Published on: June 28, 2019
Potential Clinical Applications of Pro-Resolving Lipids Mediators from Docosahexaenoic Acid
María Paz Beyer1, Luis A Videla2, Camila Farías1
1Department of Nutrition, Faculty of Medicine, University of Chile, Santiago 8380000, Chile.
Abstract:
Docosahexaenoic acid (C22:6n-3, DHA) is the precursor of specialized pro-resolving lipid mediators (SPMs), such as resolvin, protectin, and maresin families which have been considered therapeutic bioactive compounds for human health. Growing evidence indicates that DHA and SPMs are beneficial strategies in the amelioration, regulation, and duration of inflammatory processes through different biological actions. The present review discusses the reported therapeutic benefits of SPMs on various diseases and their potential clinical applications.
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