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Updated: Jul 19, 2025
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A New Single Chamber Implantable Defibrillator with Atrial Sensing: A Practical Demonstration of Sensing and Ease of Implantation
Published on: February 28, 2012
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Cardiac implantable electronic device implantation and device-related infection
Vivek Modi1, Kashyap Shah1, Bruce Ferraro1
1Department of Cardiology, St. Luke's University Health Network, Heart and Vascular Center, 801 Ostrum Street, Bethlehem, PA 18015, USA.
Summary
Device-related infections (DRI) are common complications of cardiac implantable electronic devices (CIED), with no change in prevalence. DRI is linked to high morbidity and mortality, with congestive heart failure predicting worse outcomes.
Area of Science:
- Cardiology
- Infectious Diseases
- Medical Device Technology
Background:
- Cardiac implantable electronic devices (CIED) are crucial for managing arrhythmias and preventing sudden cardiac death.
- Device-related infections (DRI) represent a significant complication, leading to adverse outcomes.
- Understanding the trends and impact of DRI is essential for patient care.
Purpose of the Study:
- To assess trends in CIED implantations.
- To evaluate the prevalence, burden, and morbidity associated with DRI.
- To identify predictors of in-hospital mortality in patients with DRI.
Main Methods:
- Utilized the 2011-2018 National Inpatient Sample database.
- Analyzed admissions for CIED implantation and DRI.
- Performed multivariate analysis to identify mortality predictors.
Main Results:
- Over 1.6 million CIED implantations and 71,007 DRI admissions were recorded.
- No significant change in annual DRI admission rates was observed (3.96-4.59%).
- Congestive heart failure, end-stage renal disease, coagulopathy, and malnutrition predicted in-hospital mortality.
Conclusions:
- Device-related infections remain a significant concern, associated with high morbidity and mortality.
- Despite technological advancements, the prevalence of DRI has not decreased.
- Identifying and managing comorbidities is crucial for improving outcomes in patients with DRI.
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