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Part Two: Perspectives on Olfactory and Gustatory Dysfunction Pathophysiology, Management, and Relevance to COVID-19:
Alternative Therapies in Health and Medicine
|August 13, 2023
Summary
Olfactory and gustatory dysfunction disorders (OGD) are not new, but COVID-19 has increased interest in their treatment. Current treatments and clinical trials show limited success for these smell and taste dysfunctions.
Area of Science:
- Otorhinolaryngology
- Infectious Diseases
- Neurology
Background:
- Olfactory and gustatory dysfunction disorders (OGD) are long-standing conditions, with renewed interest due to COVID-19.
- While not unique to COVID-19, the high incidence of OGD post-infection has spurred research into these poorly understood maladies.
Approach:
- A narrative review was conducted, searching major scientific databases and medical journals.
- Keywords included terms for smell and taste loss, OGD, specific conditions (anosmia, parosmia, ageusia), and various etiological factors and treatments.
Key Points:
- The review examines historical and current treatment strategies for OGD, irrespective of cause.
- It aims to establish a foundation for novel approaches to OGD evaluation and management.
- Limited evidence exists for effective treatments for chronic OGD.
Conclusions:
- Despite extensive research and numerous clinical trials initiated post-pandemic, significant therapeutic advancements for OGD remain elusive.
- The global demand for effective OGD treatments is unprecedented, yet current options and trials have yielded minimal results.
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