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Permanent Cerebral Vessel Occlusion via Double Ligature and Transection
Published on: July 21, 2013
The incidence of medium vessel occlusions: a population-based study
Michael Liu1, Deena Nasr1, Waleed Brinjikji1
1Mayo Clinic, Rochester, MN, United States.
Introduction:
The incidence of medium vessel occlusion (MeVO) is not well known. The objective of our study is to perform a population-based assessment to estimate the incidence of MeVOs.
Methods:
Consecutive patients from Olmsted County, Minnesota who presented for acute ischemic stroke seen at Mayo Clinic Hospital from 1/1/2018 to 12/31/2020 who were found to have a MeVO were included in this study. MeVO was defined as occlusion at or beyond the level of the middle cerebral artery M2 segment, anterior cerebral artery A2 segment, posterior cerebral artery P1 segment, and cerebellar arteries. Census data for Olmsted County was obtained from the United States Census Bureau from the year 2020.
Results:
A total of 1,718 patients were screened for the study, 77 patients fulfilled inclusion criteria to be included in the study. Presenting NIHSS was 9 (± 7). The population of Olmsted County was estimated to be 162,847. The incidence rate for MeVO was 16 cases (95% CI 12-19) per 100,000 people per year. Based on estimates of the US population in 2020 of 331,449,281 people, we estimate there are 52,236 (95% CI 40,635-64,002) new cases of MeVOs per year.
Conclusion:
As the only stroke center in Olmsted County, we have been able to estimate the incidence of ischemic stroke due to MeVO. While the incidence of MeVOs is less than both large and small vessel occlusions, they still represent a significant proportion of strokes with significant morbidity and mortality that would benefit from further studies in both acute intervention and prevention.
Insights
The incidence of medium vessel occlusion (MeVO) stroke is estimated at 16 cases per 100,000 people annually. This study provides crucial data on MeVO frequency, aiding future stroke prevention and treatment research.
Area of Science:
- Neurology
- Epidemiology
- Vascular Medicine
Background:
- Medium vessel occlusions (MeVOs) are a significant cause of ischemic stroke.
- The precise incidence of MeVOs in the general population remains poorly understood.
- Accurate incidence data is vital for understanding stroke burden and resource allocation.
Purpose of the Study:
- To estimate the population-based incidence of medium vessel occlusions (MeVOs).
- To provide a quantitative measure of MeVO frequency for epidemiological research.
- To inform future studies on MeVOs' impact on stroke morbidity and mortality.
Main Methods:
- A population-based study was conducted in Olmsted County, Minnesota.
- Consecutive patients with acute ischemic stroke and confirmed MeVO between 2018-2020 were identified.
- MeVO definition included occlusions at or beyond the M2, A2, P1 segments, or cerebellar arteries.
Main Results:
- The study identified 77 patients with MeVOs from 1,718 screened.
- The estimated incidence of MeVOs was 16 cases per 100,000 people per year.
- An estimated 52,236 new MeVO cases occur annually in the US population.
Conclusions:
- This study provides the first population-based incidence estimate for MeVOs.
- While less common than large or small vessel occlusions, MeVOs represent a substantial stroke subtype.
- Further research into acute intervention and prevention strategies for MeVOs is warranted.
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