The incidence of medium vessel occlusions: a population-based study

Michael Liu1, Deena Nasr1, Waleed Brinjikji1

  • 1Mayo Clinic, Rochester, MN, United States.

Frontiers in Neurology
|August 14, 2023
PubMed
Abstract

Insights

The incidence of medium vessel occlusion (MeVO) stroke is estimated at 16 cases per 100,000 people annually. This study provides crucial data on MeVO frequency, aiding future stroke prevention and treatment research.

Area of Science:

  • Neurology
  • Epidemiology
  • Vascular Medicine

Background:

  • Medium vessel occlusions (MeVOs) are a significant cause of ischemic stroke.
  • The precise incidence of MeVOs in the general population remains poorly understood.
  • Accurate incidence data is vital for understanding stroke burden and resource allocation.

Purpose of the Study:

  • To estimate the population-based incidence of medium vessel occlusions (MeVOs).
  • To provide a quantitative measure of MeVO frequency for epidemiological research.
  • To inform future studies on MeVOs' impact on stroke morbidity and mortality.

Main Methods:

  • A population-based study was conducted in Olmsted County, Minnesota.
  • Consecutive patients with acute ischemic stroke and confirmed MeVO between 2018-2020 were identified.
  • MeVO definition included occlusions at or beyond the M2, A2, P1 segments, or cerebellar arteries.

Main Results:

  • The study identified 77 patients with MeVOs from 1,718 screened.
  • The estimated incidence of MeVOs was 16 cases per 100,000 people per year.
  • An estimated 52,236 new MeVO cases occur annually in the US population.

Conclusions:

  • This study provides the first population-based incidence estimate for MeVOs.
  • While less common than large or small vessel occlusions, MeVOs represent a substantial stroke subtype.
  • Further research into acute intervention and prevention strategies for MeVOs is warranted.

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