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Related Experiment Videos

[Nail fold microcirculation in patients with chest malignancy].

C H Liu, J H Lin, Y Q Yao

    Zhonghua Zhong Liu Za Zhi [Chinese Journal of Oncology]
    |July 1, 1986
    PubMed
    Summary

    Cancer patients exhibit significant nail fold microcirculatory disturbances, including exudation and abnormal blood flow, regardless of malignancy type or operability. This observation highlights widespread vascular changes in advanced cancer.

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    [Research progress on animal models relevant to porto-sinusoidal vascular disease].

    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology·2025

    Area of Science:

    • Oncology
    • Microcirculation Research
    • Vascular Biology

    Context:

    • Investigates microcirculatory changes in patients with various chest malignancies.
    • Examines 90 patients including esophageal, gastric cardia, lung cancers, and neurogenic tumors.
    • Assesses the relationship between malignancy type and microcirculatory status.

    Purpose:

    • To characterize nail fold microcirculatory disturbances in patients with chest malignancies.
    • To determine if microcirculatory patterns differ among various cancer types.
    • To evaluate the potential of microcirculation observation for predicting surgical outcomes.

    Summary:

    • Marked microcirculatory disturbances were observed in cancer patients, characterized by exudation, cloudy visual fields, abnormal capillary loops, and altered blood flow.

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  • No significant differences in microcirculatory disturbances were found across different types of malignancies (esophageal, gastric cardia, lung).
  • The observed microcirculatory changes did not correlate with operability and could not predict the need for surgery.

    • Impact:

    • Highlights the presence of systemic microcirculatory dysfunction in advanced cancer.
    • Suggests that nail fold capillaroscopy may serve as a non-invasive marker for cancer-related vascular changes.
    • Provides insights into the potential pathophysiology and clinical significance of microcirculatory alterations in oncology.