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Updated: Aug 11, 2026
13:40
Examining Local Network Processing using Multi-contact Laminar Electrode Recording
Published on: September 8, 2011
12.8K
Measurable fields-to-spike causality and its dependence on cortical layer and area
Shailaja Akella1,2, André M Bastos3, Earl K Miller4
1Allen Institute, Seattle, WA, United States.
Biorxiv : the Preprint Server for Biology
|August 14, 2023
Summary
Distinct cortical layer dynamics influence brain processing. Gamma bursts in visual areas drive frontal spiking, modulating information flow across brain regions.
Area of Science:
- Neuroscience
- Computational Neuroscience
Background:
- Cortical layers exhibit distinct neuronal and local field potential (LFP) dynamics.
- The laminar processing and causal interactions between these dynamics remain under-explored.
Approach:
- Investigated laminar organization of spike-field causal flow in visual (V4) and frontal (PFC) areas of monkeys.
- Utilized event-based LFP quantification and a directed information estimator.
Key Points:
- Found area and frequency-specific laminar organization of spike-field causal connectivity.
- Gamma bursts (40-80 Hz) in superficial V4 layers drove intralaminar spiking and modulated PFC spiking.
- Information flow in PFC involved spikes influencing fields, controlling both top-down and bottom-up processing.
Conclusions:
- Spike-field causal interactions are complex across multiple brain areas and behavior.
- Laminar processing involves frequency-specific influences and hierarchical information flow.
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