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Updated: Jul 19, 2025

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
A New Perspective on Emerging Knowledge Translation Practices Comment on "Sustaining Knowledge Translation Practices:
Anita Kothari1, Jacqui Cameron2,3
1School of Health Studies, Western University, London, ON, Canada.
Knowledge translation (KT) sustainability requires ongoing network activation and strategic engagement with institutional rules. Including diverse non-researcher voices is crucial for adaptive, transformative learning in dynamic health systems.
Area of Science:
- Health Services Research
- Science and Technology Studies
- Knowledge Translation
Background:
- Borst et al. provided a critical interpretive synthesis on knowledge translation (KT) sustainability.
- This study offers an applied health services perspective on sustaining KT.
Purpose of the Study:
- To explore key elements for sustaining knowledge translation (KT) practice.
- To highlight the dynamic and interdependent nature of health ecosystems in KT.
- To emphasize the role of diverse stakeholders in KT sustainability.
Main Methods:
- Critical interpretive synthesis.
- Applied health services research perspective.
- Analysis of strategic engagement with institutional rules and network activation.
Main Results:
- KT sustainability involves continuous network activation and strategic navigation of institutional rules.
- Non-researcher voices (clinicians, administrators, policy-makers, patients, carers, public) are vital for sustaining KT.
- Health ecosystems are dynamic, necessitating repeated moments for transformative learning in KT.
Conclusions:
- Sustaining KT requires ongoing adaptation and learning within interdependent health systems.
- Integrating diverse stakeholder perspectives enhances the effectiveness and sustainability of KT practices.
- Understanding KT sustainability is an iterative process, not a singular event.
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