Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Esophageal Varices-II: Clinical Features and Management01:28

Esophageal Varices-II: Clinical Features and Management

96
Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
96
Acute Pancreatitis II: Clinical Manifestations and Management01:30

Acute Pancreatitis II: Clinical Manifestations and Management

148
Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
148
Cystic Fibrosis: Management01:24

Cystic Fibrosis: Management

194
Cystic fibrosis (CF) is an autosomal recessive disorder that predominantly affects individuals of Northern European descent, occurring at a rate of 1 in 3500. It is caused by a genetic mutation in a gene on chromosome 7, most commonly the ΔF508 mutation, that codes for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. This results in thicker mucus secretions and obstruction pathologies in multiple organs, including the lungs and sinuses.
Sinus disease and chronic...
194
Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

113
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
113
Gastritis III: Clinical Manifestations and Management01:23

Gastritis III: Clinical Manifestations and Management

326
The clinical manifestations of gastritis can vary depending on the cause and type of gastritis, but some common symptoms may include the following.
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
326
Retrovirus Life Cycles01:10

Retrovirus Life Cycles

46.2K
Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the...
46.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

British Association of Sexual Health and HIV guidelines on the management of viral hepatitis 2026.

International journal of STD & AIDS·2026
Same author

Peer-Delivered Outreach With Rapid Treatment Pathways for Hepatitis C Testing and Treatment Among Unhoused People.

Journal of viral hepatitis·2025
Same author

Rate and determinants of antiviral treatment initiation for patients with HBeAg-negative chronic hepatitis B.

Journal of viral hepatitis·2023
Same author

Age, ethnicity and proximity to clinic determine retention in care of chronic hepatitis B patients.

Journal of viral hepatitis·2022
Same author

Hepatitis B e antigen and e antibody in a multi-ethnic cohort of adult chronic hepatitis B virus patients followed at a single liver unit for a period of 20 years.

Journal of viral hepatitis·2022
Same author

Whole-genome sequencing of <i>Chlamydia trachomatis</i> isolates from persistently infected patients.

International journal of STD & AIDS·2022
Same journal

Guideline review: 2025 British Society of Gastroenterology guidelines on inflammatory bowel disease in adults - Part 2: ulcerative colitis.

Frontline gastroenterology·2026
Same journal

Guideline review: 2025 British Society of Gastroenterology guidelines on inflammatory bowel disease in adults - Part 1: Crohn's disease.

Frontline gastroenterology·2026
Same journal

Recent advances in the diagnosis and management of amoebiasis.

Frontline gastroenterology·2026
Same journal

Optimising triage of urgent referrals for suspected IBD: results from the Birmingham IBD inception study.

Frontline gastroenterology·2025
Same journal

Liver transplant assessment for hepatocellular carcinoma: a single-centre experience.

Frontline gastroenterology·2025
Same journal

Correction: Recent advances in the diagnosis and management of amoebiasis.

Frontline gastroenterology·2025
See all related articles

Related Experiment Video

Updated: Jul 19, 2025

A Three-Dimensional Spheroid Model to Investigate the Tumor-Stromal Interaction in Hepatocellular Carcinoma
12:24

A Three-Dimensional Spheroid Model to Investigate the Tumor-Stromal Interaction in Hepatocellular Carcinoma

Published on: September 30, 2021

5.3K

Hepatitis C: recent advances and practical management.

Rebecca O' Kane1, Emma Hathorn1

  • 1Queen Elizabeth Hospital Birmingham, Birmingham, UK.

Frontline Gastroenterology
|August 15, 2023
PubMed
Summary
This summary is machine-generated.

Hepatitis C virus (HCV) elimination is a global goal by 2030. Advances in direct-acting antivirals offer curative treatment, but many remain unaware of their infection, highlighting the need for improved diagnosis and management.

Keywords:
CHRONIC VIRAL HEPATITISHEPATITIS CLIVER

More Related Videos

A Protocol for Analyzing Hepatitis C Virus Replication
13:04

A Protocol for Analyzing Hepatitis C Virus Replication

Published on: June 26, 2014

24.2K
Author Spotlight: Advancements and Challenges in Hepatitis B Virus Detection
04:11

Author Spotlight: Advancements and Challenges in Hepatitis B Virus Detection

Published on: December 15, 2023

3.5K

Related Experiment Videos

Last Updated: Jul 19, 2025

A Three-Dimensional Spheroid Model to Investigate the Tumor-Stromal Interaction in Hepatocellular Carcinoma
12:24

A Three-Dimensional Spheroid Model to Investigate the Tumor-Stromal Interaction in Hepatocellular Carcinoma

Published on: September 30, 2021

5.3K
A Protocol for Analyzing Hepatitis C Virus Replication
13:04

A Protocol for Analyzing Hepatitis C Virus Replication

Published on: June 26, 2014

24.2K
Author Spotlight: Advancements and Challenges in Hepatitis B Virus Detection
04:11

Author Spotlight: Advancements and Challenges in Hepatitis B Virus Detection

Published on: December 15, 2023

3.5K

Area of Science:

  • Hepatology
  • Infectious Diseases
  • Public Health

Background:

  • Viral hepatitis, including Hepatitis C virus (HCV), causes significant global morbidity and mortality.
  • The UK has committed to the 2030 global target for viral hepatitis elimination.
  • Despite treatment advances, a substantial number of individuals remain unaware of their HCV infection.

Purpose of the Study:

  • To review recent advancements in Hepatitis C treatment and prevention strategies.
  • To provide a practical guide for managing individuals with Hepatitis C infection.
  • To support the UK's public health goals for viral hepatitis elimination.

Main Methods:

  • Literature review of recent scientific publications on HCV treatment and prevention.
  • Analysis of current HCV prevalence and awareness data in the UK.
  • Synthesis of clinical guidelines and best practices for HCV management.

Main Results:

  • Direct-acting antivirals offer short, curative oral treatment courses for Hepatitis C.
  • Treatment access has expanded in the UK, but significant undiagnosed populations persist.
  • Key challenges include increasing diagnosis rates and ensuring equitable access to care.

Conclusions:

  • Curative HCV treatments are available, necessitating strategies to identify and treat the remaining undiagnosed population.
  • Effective prevention and management approaches are crucial for achieving the 2030 viral hepatitis elimination targets.
  • A practical, integrated approach to HCV care is essential for public health impact.