Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

14
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
14
Disorders of Hemostasis01:24

Disorders of Hemostasis

991
Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
991
Venous Thrombosis I: Introduction01:30

Venous Thrombosis I: Introduction

12
Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
12
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies01:20

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

14
The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
14
Disorders of Erythrocytes01:27

Disorders of Erythrocytes

992
Disorders of erythrocytes, or red blood cells (RBCs), include a range of conditions affecting their number, shape, or function.
Erythrocyte disorders can be broadly categorized into two main types: anemic and polycythemic conditions.
A low oxygen-carrying capacity of the blood due to the loss, lower production, or destruction of erythrocytes is termed anemia. Hemorrhagic anemia, for example, occurs when bleeding from an external wound or internal ulcer reduces erythrocyte counts.
On the other...
992

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Acute Angle-Closure Glaucoma Secondary to Vitreous Prolapse Following Ocular Trauma.

Case reports in ophthalmological medicine·2026
Same author

Orbital Infarction Syndrome Following Hyaluronic Acid Lip Filler Injection.

Ophthalmic plastic and reconstructive surgery·2025
Same author

Post-LASIK Exophiala jeanselmei Keratitis.

Eye & contact lens·2024
Same author

Photographic grading to evaluate facial cleanliness and trachoma among children in Amhara region, Ethiopia.

PLoS neglected tropical diseases·2024
Same author

Geographic Representation of Authorship in Ophthalmic Research from Low- and Middle-Income Countries.

Ophthalmic epidemiology·2023
Same author

Selective effects of estradiol on human corneal endothelial cells.

Scientific reports·2023
Same journal

Acute Paracentral Scotoma Following Cosmetic Penile Filler Injection.

Retinal cases & brief reports·2026
Same journal

Intravitreous Methotrexate and Rituximab for Bilateral Diffuse Uveal Melanocytic Proliferation (BDUMP).

Retinal cases & brief reports·2026
Same journal

Multimodal imaging of ASHH in a case of Scrub Typhus Retinopathy.

Retinal cases & brief reports·2026
Same journal

Pathogenic Variants in HGSNAT associated with Autosomal Recessive Retinitis Pigmentosa without Overt Sanfilippo Syndrome.

Retinal cases & brief reports·2026
Same journal

Macular Choroidal Neovascularization in Peripapillary Hyperreflective Ovoid Mass-Like Structures (PHOMS): case report.

Retinal cases & brief reports·2026
Same journal

Endogenous Streptococcus Anginosus Endophthalmitis: A Case Report and Review of the Literature.

Retinal cases & brief reports·2026
See all related articles

Related Experiment Video

Updated: Jul 19, 2025

A Fibrin-Enriched and tPA-Sensitive Photothrombotic Stroke Model
09:42

A Fibrin-Enriched and tPA-Sensitive Photothrombotic Stroke Model

Published on: June 4, 2021

2.8K

UNILATERAL ROTH SPOTS AS AN INITIAL PRESENTATION IN ESSENTIAL THROMBOCYTHEMIA.

Fitz Gerald I Diala1,2,3, Ramoncito L Caleon4, Ali Mahdavi Fard5

  • 1UCLA Medical Scientist Training Program, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California.

Retinal Cases & Brief Reports
|August 15, 2023
PubMed
Summary
This summary is machine-generated.

Unilateral Roth spots in a young woman led to the diagnosis of essential thrombocythemia (a blood disorder). Prompt treatment with aspirin resolved her visual symptoms and fundus findings.

Keywords:
Roth spotsretinal hemorrhagethrombocythemia

More Related Videos

From a 2DE-Gel Spot to Protein Function: Lesson Learned From HS1 in Chronic Lymphocytic Leukemia
10:18

From a 2DE-Gel Spot to Protein Function: Lesson Learned From HS1 in Chronic Lymphocytic Leukemia

Published on: October 19, 2014

13.8K
Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
06:29

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques

Published on: June 11, 2019

10.4K

Related Experiment Videos

Last Updated: Jul 19, 2025

A Fibrin-Enriched and tPA-Sensitive Photothrombotic Stroke Model
09:42

A Fibrin-Enriched and tPA-Sensitive Photothrombotic Stroke Model

Published on: June 4, 2021

2.8K
From a 2DE-Gel Spot to Protein Function: Lesson Learned From HS1 in Chronic Lymphocytic Leukemia
10:18

From a 2DE-Gel Spot to Protein Function: Lesson Learned From HS1 in Chronic Lymphocytic Leukemia

Published on: October 19, 2014

13.8K
Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
06:29

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques

Published on: June 11, 2019

10.4K

Area of Science:

  • Ophthalmology
  • Hematology
  • Internal Medicine

Background:

  • Essential thrombocythemia (ET) is a myeloproliferative neoplasm characterized by elevated platelet counts.
  • ET can manifest with diverse symptoms, including ocular complications.
  • Roth spots are intraretinal hemorrhages that can indicate underlying systemic disease.

Purpose of the Study:

  • To report a case of essential thrombocythemia presenting initially with unilateral Roth spots.
  • To highlight the importance of investigating ocular findings for systemic pathology.

Main Methods:

  • A case report detailing a 25-year-old female patient.
  • Ophthalmic examination including dilated funduscopy.
  • Laboratory workup for thrombocythemia, including JAK2 mutation analysis.

Main Results:

  • The patient presented with visual disturbances and unilateral Roth spots.
  • Diagnosis of essential thrombocythemia confirmed by thrombocytosis and JAK2 (V617F) mutation.
  • Ocular findings and symptoms resolved within one month of low-dose aspirin treatment.

Conclusions:

  • Roth spots can be an early indicator of essential thrombocythemia.
  • Systemic evaluation is crucial when Roth spots are identified.
  • Early diagnosis and treatment of ET are vital due to its potential for serious complications.