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Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study
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Cancer Epidemiology in the Northeastern United States (2013-2017)
Judy R Rees1,2, Julie E Weiss2, Christine M Gunn2,3
1Department of Epidemiology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire.
Cancer Research Communications
|August 16, 2023
Summary
Northern New England (NNE) shows higher cancer incidence and mortality compared to the US. The Northeast region has higher cancer incidence but lower mortality, indicating distinct regional cancer patterns.
Area of Science:
- Epidemiology
- Public Health
- Cancer Research
Background:
- Cancer incidence and mortality rates vary geographically within the United States.
- Understanding regional differences in cancer burden is crucial for targeted public health interventions.
Purpose of the Study:
- To compare adult cancer incidence and mortality rates in the Northeast region and Northern New England (NNE) with the rest of the United States.
- To identify specific cancer types contributing to observed differences in incidence and mortality.
- To examine cancer metrics and risk factor prevalence across different race/ethnicity subgroups.
Main Methods:
- Utilized national, publicly available cancer registry data for analysis.
- Employed age-standardized cancer incidence and rate ratios (RR) for comparisons.
- Analyzed data overall and stratified by race/ethnicity.
Main Results:
- Adult cancer incidence was higher in both the Northeast (RR 1.07) and NNE (RR 1.06) compared to the US.
- Cancer mortality was lower in the Northeast (RR 0.98) but higher in NNE (RR 1.05) than the US.
- NNE exhibited higher mortality for specific cancers including brain, uterus, esophagus, lung, bladder, and melanoma.
- Higher overall cancer incidence in the Northeast was observed across most race/ethnicity subgroups.
Conclusions:
- Northern New England (NNE) presents a distinct pattern of higher cancer incidence and mortality compared to the US.
- The Northeast region shows higher cancer incidence but lower overall mortality, contrasting with NNE.
- Further research is needed to determine the underlying causes of elevated cancer incidence in the Northeast and excess mortality in NNE.
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