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Oestrogen receptor concentration and macrophage infiltration in human breast cancer
Abstract:
Oestrogen receptor concentration and percentage macrophage content were estimated in 40 human primary breast cancers. Macrophages were identified by Fc (IgG) receptor expression and by the presence of a macrophage-associated antigen. A significant inverse correlation between receptor concentration and macrophage content was found, and this was strengthened by correcting receptor level for tumour cellularity.