Related Experiment Video
Updated: Sep 5, 2026
Tissue-simulating Phantoms for Assessing Potential Near-infrared Fluorescence Imaging Applications in Breast Cancer Surgery
Published on: September 19, 2014
Exploring the impact of neoadjuvant therapy on fluorescence-guided surgery for bone and soft tissue sarcomas: A
Anne-Fleur S Verhaar1, Marc G Stevenson2, Winan J van Houdt3
1Department of Surgical Oncology, University Medical Center Groningen, Groningen, the Netherlands; TRACER Europe B.V., Groningen, the Netherlands.
Abstract:
Surgical resection is an important curative treatment for patients with bone and soft tissue sarcomas, often preceded by neoadjuvant therapy to reduce tumor size, enhance resectability and improve oncological outcomes. Fluorescence-guided surgery (FGS) has emerged as a promising technique to enhance intraoperative tumor visualization and resection precision. However, the impact of neoadjuvant therapy on the efficacy of FGS remains an area of ongoing investigation. This narrative review explores the current existing literature on the relationship between neoadjuvant therapies and the effectiveness of fluorescence-guided sarcoma surgery, identifying what has been learned from previous studies implementing FGS, and to hypothesize what is relevant for future studies.
