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Updated: Jul 19, 2025
An Approach to Enhance Alignment and Myelination of Dorsal Root Ganglion Neurons
Published on: August 24, 2016
Promoting neurite outgrowth and neural stem cell migration using aligned nanofibers decorated with protrusions and
Yingnan Liu1,2, Xiaopei Zhang1,2, Yawen Wang1,2
1Shandong Key Laboratory of Medical and Health Textile Materials, Collaborative Innovation Center for Eco-textiles of Shandong Province and the Ministry of Education, College of Textile & Clothing, Qingdao University, Qingdao 266071, China. twu@qdu.edu.cn.
Abstract:
Biomaterials integrated with both topological cues and biological modifications are urgently needed in regenerative medicine. Here, aligned nanofibrous scaffolds decorated with nanoscale SiO2 protrusions and galectin-1 coating are reported. Prospects in neurite outgrowth and neural stem cell migration are discussed for suitable use in neural tissue engineering.
