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Association between Cannabis Use Disorder and Mental Health Disorders in the Adolescent Population: A Cohort Study
Regina Muñoz-Galán1, Irene Lana-Lander1, Marta Coronado1
1Public Health Agency of Catalonia, Department of Health, Government of Catalonia, Programme on Addictions, HIV, STI and Viral Hepatitis, Barcelona, Spain.
European Addiction Research
|August 16, 2023
Summary
Young individuals in Catalonia seeking treatment for cannabis use disorder (CUD) showed a significantly higher risk of developing mental health disorders. This highlights the urgent need for targeted prevention strategies for adolescents with CUD.
Area of Science:
- Psychiatry
- Public Health
- Addiction Medicine
Background:
- Early cannabis initiation and dependent use patterns are linked to mental health disorders.
- Limited cohort studies exist on mental health development in adolescents with cannabis use disorder (CUD).
Purpose of the Study:
- To determine the cumulative incidence of mental health disorders.
- To assess the risk of developing mental health disorders in minors treated for CUD in Catalonia (2015-2019).
Main Methods:
- Retrospective fixed cohort study using the Catalan Health Surveillance System.
- Exposed cohort: minors treated for CUD (n=948); paired cohort: matched controls (n=4,737).
- Exclusion of individuals with prior mental health diagnoses; incidence rate ratios estimated using conditional Poisson models.
Main Results:
- Cumulative incidence of mental health disorders was 19.6% in the CUD cohort vs. 3.1% in the control cohort.
- The CUD cohort had an 8.7 times increased risk of developing mental health disorders.
- Higher incidence observed in females (32.7%) compared to males (15.8%); most frequent diagnoses included severe stress reactions, adjustment disorders, and personality disorders.
Conclusions:
- Adolescents treated for CUD face a significantly elevated risk of developing mental health disorders.
- Further research on CUD and associated mental health conditions is crucial for developing effective prevention strategies.
- Understanding factors contributing to CUD development is essential for public health interventions.
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