Complications in endoscopic spine surgery: a systematic review
Domenico Compagnone1, Filippo Mandelli2, Matteo Ponzo1
1IRCCS Ospedale Galeazzi Sant'Ambrogio, Milan, Italy.
Summary
This review analyzes complication rates for endoscopic spine surgeries, finding perioperative issues like nerve deficits are common in discectomy/decompression, while late complications such as implant failure occur more in fusion procedures.
Area of Science:
- Minimally Invasive Spine Surgery
- Surgical Complications
- Endoscopic Spine Procedures
Background:
- Endoscopic spine surgery offers a minimally invasive approach.
- Understanding complication profiles is crucial for patient safety and procedure optimization.
- Stratification by technique, spinal region, and procedure type is needed.
Purpose of the Study:
- To systematically review and analyze complication rates of endoscopic spine surgeries.
- To stratify complications based on surgical technique (uniportal vs. biportal), spinal district (cervical, thoracic, lumbar), and procedure type (discectomy/decompression vs. fusion).
Main Methods:
- Systematic review adhering to PRISMA guidelines.
- Comprehensive literature search across multiple databases (MEDLINE, EMBASE, etc.).
- Inclusion of observational studies and randomized controlled trials; exclusion of reviews and abstracts. Data extraction on perioperative and late complications.
Main Results:
- Analysis included 117 articles covering 20,020 patients (10,405 UESS, 9615 UBESS).
- Uniportal full-endoscopic spine surgery (UESS) and unilateral biportal endoscopic spine surgery (UBESS) were compared.
- Complication data were analyzed in subgroups with at least 100 patients for statistical validity.
Conclusions:
- Perioperative complications (e.g., dural tear, transient neurological deficit) are significant in endoscopic discectomy and decompression.
- Late complications, notably mechanical implant failure, are more prevalent in endoscopic interbody fusion procedures.
- Findings provide insights into the risk profiles of different endoscopic spine surgery techniques and procedures.


