Related Experiment Video
Updated: Jul 19, 2025
Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
Provocative mesenteric angiography for occult gastrointestinal bleeding: a systematic review
Siddhi Hegde1, Patrick D Sutphin2, Omar Zurkiya2
1Division of Interventional Radiology, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. siddhi.hegde5@gmail.com.
Provocative mesenteric angiography aids in diagnosing obscure gastrointestinal bleeding (GIB). While effective, further high-level studies are needed to confirm its safety and optimal use in clinical practice.
Area of Science:
- Gastroenterology
- Interventional Radiology
Background:
- Occult gastrointestinal bleeding (GIB) presents diagnostic and therapeutic challenges for clinicians.
- Accurate localization is crucial for effective management of GIB.
Purpose of the Study:
- To systematically review the utility of provocative mesenteric angiography (PMA) in diagnosing and localizing occult GIB.
- To assess the efficacy and safety of PMA based on existing literature.
Main Methods:
- A systematic literature search was performed on PubMed and Embase up to January 1, 2023.
- Included studies focused on patients undergoing PMA for occult GIB diagnosis.
- Twenty-seven articles involving 230 patients were analyzed.
Main Results:
- The overall positivity rate for provocative angiography was 48.7%.
- Heparin administration showed a higher positivity rate (58%) compared to thrombolytics (46.7%).
- Interventional procedures included embolization (46.4%) and surgery (37.5%), with rare complications.
Conclusions:
- Provocative mesenteric angiography (PMA) demonstrates potential as a diagnostic and therapeutic tool for occult GIB.
- Further high-level evidence and standardized protocols are essential to establish PMA's safety and optimize its application.
More Related Videos
07:12Targeting the Rat's Small Bowel: Long-Term Infusion into the Superior Mesenteric Artery
Published on: April 8, 2021
04:01Indocyanine Green-Guided Intraoperative Imaging to Facilitate Video-Assisted Retroperitoneal Debridement for Treating Acute Necrotizing Pancreatitis
Published on: September 8, 2022
Related Concept Videos
01:28Esophageal Varices-II: Clinical Features and Management
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
01:24Esophageal Varices-I: Introduction
01:29Appendicitis-II: Diagnostic Studies and Management
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
01:28Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
01:23Gastritis III: Clinical Manifestations and Management
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...