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Drug Delivery: Overview01:16

Drug Delivery: Overview

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The selection of a drug's delivery route depends upon its physicochemical properties, including lipid or water solubility and ionization, as well as the therapeutic requirement, such as immediate or sustained effect. These routes can be divided into three primary categories: enteral, parenteral, and topical.
Enteral delivery involves administering drugs directly through swallowing, sublingual placement, or buccal application. Orally administered drugs predominantly navigate the...
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Drug delivery methods like oral inhalation, nasal sprays, transdermal patches, eye drops, intravitreal injection,  and rectal administration provide localized effects with reduced toxicity.
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Local Anesthetics: Common Agents and Their Applications01:23

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Local anesthetics (LAs) are commonly used for various applications in medical and dental procedures. Some of the common agents used are cocaine, lidocaine, and bupivacaine.
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Drug administration involves delivering drugs to the body through various routes, such as enteral, parenteral, and topical.
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Choosing the appropriate route of drug administration is significantly influenced by two key factors: the therapeutic objectives and the inherent properties of the drug being used.
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The administration of drugs via parenteral routes allows for direct drug introduction into the systemic circulation, resulting in high bioavailability because the medication bypasses the harsh conditions of the gastrointestinal tract and hepatic metabolism.
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Topical Vehicles: A Dermatologist's Perspective.

Stephanie Adame1, Michael E Collins2, Abraham M Korman3

  • 1Ohio State University College of Medicine, The Ohio State University Wexner Medical Center, Columbus, Ohio. Stephanie.adame@osumc.edu.

International Journal of Pharmaceutical Compounding
|August 18, 2023
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Summary
This summary is machine-generated.

Choosing the right topical vehicle is crucial for effective dermatologic treatment. This article reviews common topical vehicles, highlighting their pros and cons for various skin conditions.

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Area of Science:

  • Dermatology
  • Pharmaceutics

Background:

  • Topical treatments are fundamental for managing numerous dermatologic conditions.
  • The selection of an appropriate topical vehicle is a critical component of successful treatment regimens.

Approach:

  • This article provides a comprehensive review of commonly utilized topical vehicles in dermatologic practice.
  • The review considers factors influencing vehicle selection, including patient preference and anatomical site.

Key Points:

  • Different topical vehicles possess distinct advantages and disadvantages.
  • Understanding these characteristics is essential for optimizing therapeutic outcomes.
  • Common vehicles like ointments, creams, lotions, and gels are discussed.

Conclusions:

  • The appropriate selection of topical vehicles significantly impacts treatment efficacy.
  • Consideration of vehicle properties and patient-specific factors enhances therapeutic success in dermatology.