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Tumor microenvironment, histone modifications, and myeloid-derived suppressor cells

Xinyu Tian1, Ting Wang2, Han Shen3

  • 1Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing, China; Department of Immunology, Jiangsu Key Laboratory of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, China.

Cytokine & Growth Factor Reviews
|August 19, 2023
PubMed
Summary

Histone modifications in myeloid-derived suppressor cells (MDSCs) are key epigenetic regulators within the tumor microenvironment (TME). Understanding these modifications offers new strategies to reverse tumor-induced immunosuppression.

Keywords:
Epigenetic therapyHistone modificationsMyeloid-derived suppressor cellsTumor microenvironment

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