Related Experiment Video
Updated: Jul 18, 2025

Micro-dissection of Enamel Organ from Mandibular Incisor of Rats Exposed to Environmental Toxicants
Published on: March 29, 2018
Worldwide prevalence of natal and neonatal teeth: Systematic review and meta-analysis
Insights
Natal teeth affect approximately 1 in 289 newborns, while neonatal teeth occur in about 1 in 2,212. Healthcare providers should be vigilant for these conditions, as early detection of natal and neonatal teeth is crucial for prompt intervention.
Area of Science:
- Pediatric Dentistry
- Neonatal Care
- Oral Health Epidemiology
Background:
- Identifying natal and neonatal teeth in newborns is critical due to potential immediate care needs.
- This systematic review and meta-analysis aimed to establish the global prevalence of natal and neonatal teeth.
Approach:
- A comprehensive search of six electronic databases and gray literature was conducted on February 23, 2023.
- Observational studies reporting prevalence were included; studies lacking prevalence data or equating natal and neonatal teeth were excluded.
- Methodological quality was assessed using the Joanna Briggs Institute checklist, and prevalence was estimated using a β-binomial proportion meta-analysis.
Key Points:
- The worldwide prevalence of natal teeth was estimated at 34.55 per 10,000 (95% CI, 20.12 to 59.26).
- The worldwide prevalence of neonatal teeth was estimated at 4.52 per 10,000 (95% CI, 2.59 to 17.91).
- Prevalence varied significantly by continent, with natal teeth ranging from 11.26 (Asia) to 75.32 (North America) per 10,000, and neonatal teeth from 3.52 (Europe) to 6.01 (South America) per 10,000.
Conclusions:
- Natal teeth affect approximately 1 in 289 newborns, and neonatal teeth affect about 1 in 2,212.
- Despite the low prevalence, healthcare professionals must remain alert for these conditions, which often necessitate immediate dental care.
Background:
Identifying the presence of teeth in newborns is important as it may require immediate care. This study aimed to determine the worldwide prevalence of natal and neonatal teeth.
Type Of Studies Reviewed:
Six electronic databases and the gray literature were searched on February 23, 2023 to identify observational studies reporting the prevalence of natal or neonatal teeth. Studies assuming natal and neonatal teeth as identical terms or not reporting prevalence indicators were excluded. The methodological quality of the studies was assessed using the Joanna Briggs Institute checklist for studies reporting prevalence data. The worldwide prevalence of natal and neonatal teeth was estimated via proportion meta-analysis using a β-binomial model. Heterogeneity across studies was explored via subgroup analyses and meta-regression.
Results:
None of the 23 included studies fulfilled all items of the methodological quality checklist. The worldwide prevalence of natal teeth was 34.55 (95% CI, 20.12 to 59.26) per 10,000, and the prevalence of neonatal teeth was 4.52 (95% CI, 2.59 to 17.91) per 10,000. Subgroup analysis by continent showed that the prevalence of natal teeth ranged from 11.26 (95% CI, 7.58 to 16.61) per 10,000 in Asia through 75.32 (95% CI, 51.11 to 99.86) per 10,000 in North America, and the prevalence of neonatal teeth ranged from 3.52 (95% CI, 1.73 to 7.06) per 10,000 in Europe through 6.01 (95% CI, 2.25 to 16.60) per 10,000 in South America. Meta-regression did not find a statistically significant association between prevalence rates and year of publication or sample size.
Practical Implications:
Approximately 1 in 289 newborns had natal teeth and 1 in 2,212 had neonatal teeth. Although this is not a high prevalence, professionals must be alert to identify these conditions, which often require immediate care.
Related Concept Videos
Teeth
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
Tooth Anatomy
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
Prevalence and Incidence
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
Assessment of the Mouth
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
Bias in Epidemiological Studies
Teratogenicity

