Related Experiment Video
Updated: Jul 18, 2025

New Thrombectomy Technique for Total Portal Vein Thrombosis in Liver Transplantation
Published on: June 27, 2025
Fulminant Presentation of Budd-Chiari Syndrome Secondary to COVID-19 Infection
Harshavardhan Sanekommu1, Sobaan Taj1, Catherine Kilada2
1Department of Medicine, Jersey Shore University Medical Center, Neptune City, NJ.
Insights
Budd-Chiari syndrome (BCS), a rare hepatic venous outflow obstruction, can be triggered by COVID-19. This case highlights a young man with BCS and portal vein thrombosis due to COVID-19, emphasizing transplant consideration for non-responsive cases.
Area of Science:
- Hepatology
- Vascular Medicine
- Infectious Diseases
Background:
- Budd-Chiari syndrome (BCS) involves hepatic venous outflow obstruction, a rare condition.
- Hypercoagulability states, both inherited and acquired, are critical considerations in new BCS cases.
- COVID-19 is known to induce hypercoagulability, but its link to BCS is infrequent.
Abstract:
Budd-Chiari syndrome (BCS) is a rare condition characterized by the obstruction of hepatic venous outflow. It is estimated to affect 1 in 100,000 people worldwide. In cases of new BCS, inherited and acquired hypercoagulability states must be evaluated. Coronavirus disease 2019 (COVID-19) can induce a hypercoagulable state because of its extensive inflammatory response, and while it has been reported to cause portal vein thrombosis, it rarely causes BCS. This article presents a case of a 22-year-old man who developed fulminant symptoms and was subsequently diagnosed with BCS and portal vein thrombosis secondary to COVID-19 infection, after ruling out other inherited and acquired causes of BCS. In addition, a literature review is provided to understand the presentation and management of such patients. Although most patients improve with medical management, this article emphasizes the consideration of liver transplant for patients who do not improve.
More Related Videos
Related Concept Videos
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
Pleural Effusion II: Symptoms and Management
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
Endocarditis II: Clinical Features of Infective Endocarditis
Acute Pancreatitis II: Clinical Manifestations and Management
Esophageal Varices-II: Clinical Features and Management
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...

