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Association Between the Use of Systemic Steroids and Ocular Hypertension as a Side Effect in Pediatric Population: A

Ujala Mushtaq1, Basim Shaman Ameen1, Chuhao Nie1

  • 1Research, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.

Cureus
|August 21, 2023
PubMed

Insights

Systemic steroid use in children frequently causes ocular hypertension (increased eye pressure). Healthcare providers should monitor children for this common side effect, especially within the first month of treatment.

Area of Science:

  • Pediatric Endocrinology
  • Ophthalmology
  • Pharmacology

Background:

  • Systemic steroids are widely prescribed for pediatric conditions.
  • Ocular hypertension (OHT) is a known side effect of steroid use.
  • Limited data exists on OHT in children receiving systemic steroids.

Purpose of the Study:

  • To determine the incidence of OHT in children using systemic steroids.
  • To identify risk factors associated with OHT development in this population.

Main Methods:

  • A comprehensive literature search was performed across PubMed, PMC, Medline, and CDSR.
  • Twelve articles were selected after screening and quality assessment for review.

Main Results:

  • Ocular hypertension (OHT) is a common adverse effect of systemic steroid therapy in children.
  • OHT often develops within one month of initiating steroid treatment.
  • Several risk factors contributing to OHT development were identified.

Conclusions:

  • Systemic steroid administration in children is associated with a significant risk of developing OHT.
  • Increased awareness among healthcare professionals is crucial for early detection and management.
  • Guidelines for regular eye examinations in children on long-term systemic steroids are recommended.

Keywords:
childrenocular hypertension (oht)raised intra-ocular pressureside effectssystemic steroids

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