Related Experiment Video

Updated: Jul 18, 2025

Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers
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Published on: September 20, 2018

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The nuclear pore complex as a platform for epigenetic regulation.

Jason H Brickner1

  • 1Department of Molecular Biosciences, Northwestern University, Evanston, IL, USA.

The Journal of Cell Biology
|August 21, 2023
PubMed
Summary

The nuclear pore complex (NPC) regulates gene expression by interacting with chromatin. This study reveals how NPC-mediated epigenetic silencing involves the replication factor PCNA.

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