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Related Experiment Video

Updated: Jul 18, 2025

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TIPS: indications, Contraindications, and Evaluation.

Allison Carroll1,2, Justin R Boike3

  • 1Department of Medicine, Division of Gastroenterology & Hepatology, Northwestern University Feinberg School of Medicine, 676 N. St. Clair, Suite 1900, Chicago, IL, 60611, USA.

Current Gastroenterology Reports
|August 21, 2023
PubMed
Summary

Transjugular intrahepatic portosystemic shunts (TIPS) are expanding in use for liver conditions like hepatorenal syndrome. Newer stent technology improves outcomes and patient selection for TIPS procedures.

Keywords:
AscitesHepatic EncephalopathyPortal HypertensionTIPS

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Area of Science:

  • Interventional Radiology
  • Hepatology
  • Gastroenterology

Background:

  • Transjugular intrahepatic portosystemic shunt (TIPS) procedures have evolved significantly over three decades.
  • Advancements include the development of controlled-expansion, covered stents, broadening clinical applications.

Purpose of the Study:

  • To review current and emerging indications, contraindications, and evaluation for TIPS.
  • To highlight the impact of technological advancements on TIPS utility.

Main Methods:

  • Literature review of recent findings and technological progress in TIPS.
  • Analysis of expanded clinical uses and outcomes associated with newer stent technology.

Main Results:

  • Indications for TIPS have expanded to include hepatorenal syndrome, hepatopulmonary syndrome, and pre-abdominal surgery patients.
  • Controlled-expansion, covered stents have reduced post-TIPS hepatic encephalopathy, increasing patient eligibility.
  • Overall clinical utility and potential of TIPS have rapidly expanded due to new stent technology and research.

Conclusions:

  • Ongoing research and randomized-controlled trials are essential for optimizing patient selection and validating emerging indications for TIPS.
  • Technological advancements continue to enhance the effectiveness and safety of TIPS procedures.