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Updated: Aug 2, 2026

05:03
Establishing a Silicosis Rat Model via Exposure of Whole-Body to Respirable Silica
Published on: October 28, 2022
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Occupational Silica Exposure as a Potential Risk for Microscopic Polyangiitis
Alper Alp1, Melike Ersoy2, İbrahim Meteoğlu3
1Department of Nephrology, Faculty of Medicine, Mugla Sıtkı Koçman University, Mugla, Turkey.
Wilderness & Environmental Medicine
|August 21, 2023
Summary
Silica exposure can cause microscopic polyangiitis, a serious condition affecting blood vessels. This case highlights the importance of considering occupational silica exposure in patients with unexplained kidney dysfunction.
Area of Science:
- Nephrology
- Rheumatology
- Occupational Medicine
Background:
- Microscopic polyangiitis (MPA) is a key vasculitis associated with cytoplasmic antibodies.
- MPA can cause significant morbidity and mortality.
- The exact cause of MPA remains unclear, but environmental factors are suspected.
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