The Influence of Modifiable Risk Factors on Postoperative Outcomes in Patients Receiving Surgery for Resection for...

Area of Science:

• Neurosurgery
• Surgical Oncology
• Public Health

Background:

• Acoustic neuromas, common cerebellopontine angle tumors, significantly impair quality of life.
• Microsurgical resection is the primary treatment, but perioperative outcomes influenced by modifiable risk factors (MRFs) are under-researched.
• Understanding MRFs' impact is vital for optimizing patient care and surgical planning.

Purpose of the Study:

• To investigate the association between MRFs (malnutrition, obesity, dyslipidemia, uncontrolled hypertension, smoking) and postoperative outcomes.
• To determine if MRFs predict nonroutine discharge and hospital readmission after acoustic neuroma resection.
• To identify which MRFs have the most significant impact on perioperative complications.

Main Methods:

• Utilized the 2016-2017 Healthcare Cost and Utilization Project Nationwide Readmissions Database.
• Queried MRFs using International Classification of Diseases, Tenth Revision (ICD-10) codes.
• Employed logistic regression and Mann-Whitney U tests for statistical analysis, with RStudio and Epitools package.

Main Results:

• Malnutrition was a stronger predictor of nonroutine discharge than other MRFs or no MRFs (P < .05).
• Malnutrition models outperformed obesity and smoking models for readmission prediction (P < .05).
• Dyslipidemia models showed increased predictive power compared to obesity, smoking, or uncontrolled hypertension.

Conclusions:

• This study is the first to examine MRFs in acoustic neuroma surgery patients.
• Certain modifiable risk factors, particularly malnutrition, significantly complicate the perioperative course.
• Findings highlight the importance of assessing and managing MRFs to improve surgical outcomes.