Related Experiment Video
Updated: Jul 18, 2025
Isolation of Adipose Derived Regenerative Cells for the Treatment of Erectile Dysfunction Following Radical Prostatectomy
Published on: December 28, 2021
Open Pilot Study on the Rejuvenation Effect of Absorbable Threads in the Genital Area
Irina Poleva1, Natalia Markova2, Marlen Sulamanidze3
1UNICAM, School of Pharmaceutical and Health Sciences, Camerino, Italy.
Purpose:
We propose a new method of genital rejuvenation based on absorbable thread insertion. In this study, we aimed to assess the safety and efficacy of particular absorbable threads made of P (LA/CL), the so-called Nano Spring 7, for vulvar rejuvenation.
Patients And Methods:
The study was conducted in two parts: the first by anatomical dissection and the second by clinical study. The first part of the study clarified safety and efficacy of thread insertion in this anatomical area. During the second part, 19 patients underwent Nano Spring 7 absorbable thread insertion in the subcutaneous layer of the labia majora to improve esthetic parameters and were followed up after 7, 30, 90, and 180 days. We evaluated outcomes using four different patients' questionnaires and one investigator's questionnaire.
Results:
The anatomical dissection defined the correct anatomical layer of threads implantation and the subcutaneous structures allowing for the thread anchoring. All the patients completed the study. The patients' and investigators' subjective evaluations during follow-up and at the end of the study were very positive. All the patients showed a decrease in discomfort sensations related to the labia majora conditions and aesthetic improvement in the vulvar area and recommended the treatment to their friends.
Conclusion:
The use of absorbable threads is an innovative, safe minimally invasive approach to genital rejuvenation.
