Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Translation01:31

Translation

15.0K
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of Life
Proteins are...
15.0K
Termination of Translation01:44

Termination of Translation

5.5K
5.5K
Forgetting01:21

Forgetting

99
Forgetting is an intrinsic aspect of human memory, characterized by the gradual loss or inaccessibility of information over time. Hermann Ebbinghaus, a pioneering psychologist, extensively studied this phenomenon and formulated the forgetting curve. This curve illustrates that memory loss occurs rapidly immediately after learning and then decelerates over time. Several mechanisms contribute to forgetting, including encoding failure, storage decay, retrieval failure, and interference.
Encoding...
99
Cotranslational Protein Translocation01:20

Cotranslational Protein Translocation

7.4K
Translocation of proteins across membranes is an ancient process that occurs even in bacteria and archaebacteria. In fact, the components of the translocation machinery are still conserved between prokaryotes and eukaryotes.
Sec61 channel partners for cotranslational translocation
During cotranslational translocation, the Sec61 channel partners with the signal recognition particle (SRP), the signal recognition particle receptor (SR), and the ribosomes to transport the nascent polypeptide chain...
7.4K
Latitudes and Departures01:27

Latitudes and Departures

134
Latitudes and departures are essential concepts in surveying, providing a systematic way to analyze the projections of traverse lines. These projections allow surveyors to interpret a line's north-south and east-west components, which are crucial for precisely calculating areas, bearings, and lengths. Latitude is the north-south projection of a line, calculated as the product of the line's length and the cosine of its bearing. Departure, conversely, is the east-west projection obtained by...
134
Traveling Waves: Lossless Lines01:27

Traveling Waves: Lossless Lines

157
The provided content explores the behavior of traveling waves on single-phase lossless transmission lines. It begins with a single-phase two-wire lossless transmission line of length Δx, characterized by a loop inductance LH/m and a line-to-line capacitance C F/m. These parameters result in a series inductance LΔx  and a shunt capacitance CΔx.
157

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Miracle.

Cambridge quarterly of healthcare ethics : CQ : the international journal of healthcare ethics committees·2025
Same author

Ghost in the Machine.

Cambridge quarterly of healthcare ethics : CQ : the international journal of healthcare ethics committees·2024
Same author

Written in Stone.

Cambridge quarterly of healthcare ethics : CQ : the international journal of healthcare ethics committees·2024
Same author

Double Talk.

Cambridge quarterly of healthcare ethics : CQ : the international journal of healthcare ethics committees·2022
Same author

The Spark.

Cambridge quarterly of healthcare ethics : CQ : the international journal of healthcare ethics committees·2021
Same author

Truth Be Damned.

Cambridge quarterly of healthcare ethics : CQ : the international journal of healthcare ethics committees·2021
Same journal

Sentience. Not Necessarily a Problem?

Cambridge quarterly of healthcare ethics : CQ : the international journal of healthcare ethics committees·2026
Same journal

No Need to Feel.

Cambridge quarterly of healthcare ethics : CQ : the international journal of healthcare ethics committees·2026
Same journal

The One Health Paradigm and Wild Animal Welfare Science.

Cambridge quarterly of healthcare ethics : CQ : the international journal of healthcare ethics committees·2026
Same journal

From Mollusks to Machines: An Ethical Framework Focused on the Urgency of Extreme Suffering.

Cambridge quarterly of healthcare ethics : CQ : the international journal of healthcare ethics committees·2026
Same journal

Sentience and Why It Matters.

Cambridge quarterly of healthcare ethics : CQ : the international journal of healthcare ethics committees·2026
Same journal

The Wrong Motives for Potentially Harming a Being.

Cambridge quarterly of healthcare ethics : CQ : the international journal of healthcare ethics committees·2026
See all related articles

Related Experiment Video

Updated: Jul 18, 2025

Exploring the Use of Isolated Expressions and Film Clips to Evaluate Emotion Recognition by People with Traumatic Brain Injury
05:51

Exploring the Use of Isolated Expressions and Film Clips to Evaluate Emotion Recognition by People with Traumatic Brain Injury

Published on: May 15, 2016

9.1K

Lost in Translation.

Robert A Burton1

  • 1Independent Scholar, Sausalito, CA, USA.

Cambridge Quarterly of Healthcare Ethics : CQ : the International Journal of Healthcare Ethics Committees
|August 22, 2023
PubMed
Summary
This summary is machine-generated.

Scleroderma is a progressive autoimmune disease causing skin and joint tightening. Biomarkers indicate a worsening prognosis, potentially involving multiple organs and gastrointestinal symptoms.

More Related Videos

Analysis of Translation Initiation During Stress Conditions by Polysome Profiling
10:59

Analysis of Translation Initiation During Stress Conditions by Polysome Profiling

Published on: May 19, 2014

18.3K
In vivo Interrogation of Central Nervous System Translatome by Polyribosome Fractionation
09:13

In vivo Interrogation of Central Nervous System Translatome by Polyribosome Fractionation

Published on: April 30, 2014

12.4K

Related Experiment Videos

Last Updated: Jul 18, 2025

Exploring the Use of Isolated Expressions and Film Clips to Evaluate Emotion Recognition by People with Traumatic Brain Injury
05:51

Exploring the Use of Isolated Expressions and Film Clips to Evaluate Emotion Recognition by People with Traumatic Brain Injury

Published on: May 15, 2016

9.1K
Analysis of Translation Initiation During Stress Conditions by Polysome Profiling
10:59

Analysis of Translation Initiation During Stress Conditions by Polysome Profiling

Published on: May 19, 2014

18.3K
In vivo Interrogation of Central Nervous System Translatome by Polyribosome Fractionation
09:13

In vivo Interrogation of Central Nervous System Translatome by Polyribosome Fractionation

Published on: April 30, 2014

12.4K

Area of Science:

  • Rheumatology
  • Immunology
  • Dermatology

Background:

  • Scleroderma is a complex autoimmune condition.
  • Characterized by hardening and tightening of the skin and connective tissues.
  • Can affect internal organs, leading to significant morbidity.

Purpose of the Study:

  • To describe the clinical presentation of scleroderma.
  • To highlight the prognostic implications of biomarkers.
  • To outline potential disease progression and complications.

Main Methods:

  • Clinical examination of affected limbs.
  • Review of patient biomarkers.
  • Discussion of expected disease trajectory and symptoms.

Main Results:

  • Diagnosis of scleroderma confirmed.
  • Biomarkers suggest a progressive disease course.
  • Anticipated symptoms include skin/joint tightening, GI issues, and organ involvement.

Conclusions:

  • Scleroderma diagnosis requires careful clinical assessment.
  • Prognosis is influenced by specific biomarkers.
  • Patient education on potential complications is crucial for management.