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Updated: Jul 18, 2025

Author Spotlight: Enhancing Coronary Artery Revascularization
Published on: September 15, 2023
Emergency coronary artery bypass surgery in octogenarians with acute coronary syndrome: off and on pump
E E Tekin1, B Aydinli, M A Yesiltas
1Department of Cardiovascular Surgery, Mersin City Training and Research Hospital, Mersin, Turkey. dresraer@yahoo.com.
Insights
Emergency off-pump coronary artery bypass surgery (CABG) is safer for octogenarians with acute coronary syndrome (ACS). This approach reduces complications like stroke and renal failure compared to on-pump surgery.
Area of Science:
- Cardiac Surgery
- Cardiology
- Geriatric Medicine
Background:
- Cardiac surgery risks increase with age, particularly in octogenarians with comorbidities.
- Emergency coronary artery bypass surgery (CABG) for acute coronary syndrome (ACS) carries higher mortality and morbidity than elective procedures.
- Comparing off-pump (OPCAB) versus on-pump (ONCAB) techniques in this high-risk group is crucial.
Purpose of the Study:
- To compare the outcomes of off-pump coronary bypass (OPCAB) and on-pump coronary bypass surgery (ONCAB).
- To evaluate the effectiveness of OPCAB versus ONCAB in octogenarians undergoing emergency CABG for ACS.
- To identify the optimal revascularization strategy for reducing postoperative complications in elderly ACS patients.
Main Methods:
- Retrospective analysis of 383 octogenarians undergoing isolated emergency CABG due to ACS.
- Patients were divided into two groups: OPCAB (n=130) and ONCAB (n=253).
- Preoperative, intraoperative, and postoperative data were collected and compared between the groups.
Main Results:
- ONCAB patients experienced significantly longer intensive care unit and hospital stays.
- ONCAB group showed higher rates of erythrocyte suspension transfusion, low cardiac output syndrome, acidosis, acute renal failure, and stroke.
- OPCAB was associated with fewer major postoperative complications compared to ONCAB.
Conclusions:
- Emergency OPCAB is a more advantageous revascularization option for elderly patients with ACS.
- OPCAB significantly reduces the risk of major postoperative complications in this high-risk population.
- This study supports OPCAB as a preferred strategy for octogenarians with ACS requiring emergency CABG.
Objective:
The risk of operation in cardiac surgery increases logarithmically with advanced age. In older individuals, additional comorbidities compel the clinician to deal with postoperative complications. The mortality and morbidity rates of emergency coronary artery bypass surgery (CABG) in the presence of acute coronary syndrome (ACS), or just after it, are higher than those of elective surgeries. In our study, we compared the outcomes of off-pump coronary bypass (OPCAB) and on-pump coronary bypass surgery (ONCAB) in this high-risk subgroup.
Patients And Methods:
383 octogenarians who underwent isolated emergency CABG due to ACS were divided into two groups according to the coronary bypass technique. Group 1 (off-pump) median age (IQR) 84 years (min: 80-max: 99, n = 130); Group 2, (on-pump) median age 85 years (min: 80-max: 89, n=253). Preoperative, intraoperative, and postoperative data were collected retrospectively on standard variables. OPCAB and ONCAB outcomes were compared.
Results:
ONCAB patients had a significantly longer intensive care unit stay, longer hospital stay, more transfused erythrocyte suspension, more low cardiac output syndrome and acidosis, a higher rate of acute renal failure and a higher rate of stroke than OPCAB patients (respectively; p=0.003; p=0.008; p=0.002; p=0.031; p=0.038, p=0.022, respectively).
Conclusions:
We showed that emergency OPCAB as a revascularization option in elderly patients with acute coronary syndrome is more advantageous in terms of preventing major postoperative complications.
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