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Quantification of Diabetes-induced Adherent Leukocytes in Retinal Vasculature
Published on: January 24, 2025
333
PSORIASIS INCREASES RETINAL VEIN OCCLUSION RISK IN DIABETIC PATIENTS: A Nationwide Population-Based Study
Mee Yon Lee1, Kyungdo Han2, Ha Yeh Rin Koo3
1Department of Ophthalmology, College of Medicine, The Catholic University of Korea, Republic of Korea.
Retina (Philadelphia, Pa.)
|August 22, 2023
Summary
Psoriasis increases the risk of retinal vein occlusion (RVO) in patients with type 2 diabetes. This study highlights the need for increased vigilance for RVO in diabetic individuals with psoriasis.
Area of Science:
- Ophthalmology
- Dermatology
- Endocrinology
Background:
- Psoriasis is a chronic inflammatory disease.
- Retinal vein occlusion (RVO) is a serious complication affecting the eye's vasculature.
- Diabetes Mellitus (DM) is a known risk factor for various vascular complications.
Purpose of the Study:
- To investigate the association between psoriasis and the incidence of RVO.
- To determine if psoriasis is an independent risk factor for RVO in patients with Type 2 Diabetes Mellitus (DM).
Main Methods:
- A retrospective, nationwide, population-based cohort study was conducted.
- Medical records of Type 2 DM patients aged ≥20 years from January 2009 to December 2012 were analyzed.
- Incidence of RVO was compared between patients with and without psoriasis until December 2018.
Main Results:
- The study included 2,745,689 Type 2 DM patients (23,725 with psoriasis).
- The incidence rate of RVO was higher in the psoriasis group (3.14/1,000 person-years) compared to the control group (2.44/1,000 person-years).
- Psoriasis was associated with a significantly increased risk of RVO (Hazard Ratio: 1.216, 95% CI: 1.11-1.33).
Conclusions:
- Psoriasis is an independent risk factor for developing RVO in patients with Type 2 DM.
- Healthcare providers should monitor diabetic patients with psoriasis closely for signs of RVO.
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