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Activated Cross-linked Agarose for the Rapid Development of Affinity Chromatography Resins - Antibody Capture as a Case Study
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Model-assisted process development, characterization and design of continuous chromatography for antibody separation

Yan-Na Sun1, Wu-Wei Chen1, Shan-Jing Yao1

  • 1Key Laboratory of Biomass Chemical Engineering of Ministry of Education, Zhejiang Key Laboratory of Smart Biomaterials, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310058, China.

Journal of Chromatography. A
|August 22, 2023
PubMed
Summary

Continuous chromatography is key for manufacturing monoclonal antibodies. Model-assisted approaches streamline development by investigating parameters and optimizing processes, reducing time and resources.

Keywords:
Continuous chromatographyModel-assisted approachProcess characterizationProcess designProcess development

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