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Updated: Jul 18, 2025

The Measurement and Treatment of Suppression in Amblyopia
Published on: December 14, 2012
Early management of capillary haemangioma to prevent stimulus-deprivation amblyopia
1Raj Eye Hospital, Gorakhpur, India.
Insights
A combination therapy of intralesional steroids, oral propranolol, and topical timolol effectively treated infantile capillary haemangiomas. This approach rapidly reduced infantile haemangioma size and prevented vision complications.
Area of Science:
- Ophthalmology
- Pediatric Dermatology
- Vascular Lesion Treatment
Background:
- Infantile capillary haemangiomas (IHs) are common benign tumors, frequently affecting the head and neck.
- Left upper eyelid IHs can lead to stimulus-deprivation amblyopia due to obstructed vision.
Observation:
- A 3-month-old infant presented with an upper eyelid IH causing visual obstruction.
- Treatment involved intralesional Triamcinolone acetate, oral propranolol, and topical timolol.
- No adverse effects were noted during the treatment period.
Findings:
- The combination therapy resulted in a marked reduction in IH size.
- Immediate relief was observed for the infant's visual obstruction.
- The treatment successfully mitigated the risk of amblyopia.
Implications:
- Combined intralesional steroids, oral propranolol, and topical timolol offer an effective treatment for IHs.
- This therapeutic strategy provides a rapid response and prevents potential vision impairment.
- Early intervention with this multimodal approach is crucial for managing eyelid IHs.
Introduction:
Infantile capillary haemangiomas (IHs) are common, benign tumours that are self -limiting and generally found in the head and neck region.
Case:
We present a case of a three month old female baby who presented with a left upper eyelid capillary haemangioma because of which she could not lift the upper lid subjecting her to a high risk of stimulus- deprivation amblyopia. Treatment was provided in the form of an intralesional Triamcinolone acetate injection (40 mg/ml) under general anaesthesia, along with oral Propranolol (1 mg/kg body in 2 divided doses for the first two days, followed by 2 mg/kg in 2 divided doses for ten days (continued upto four months) and topical Timolol (0.5%) lid massage twice a day upto a period of six months.
Observation:
No adverse effects were reported and a marked reduction in size of the tumor was observed thereby providing an immediate relief to the child.
Conclusion:
Hence a combination therapy using intralesional steroids, along with oral propranolol and topical timolol over the lesion has proven to be very effective in providing early response.

