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Related Concept Videos

Flow Cytometry01:23

Flow Cytometry

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The development of flow cytometry techniques began in 1934 with initial attempts by Andrew Moldavan, a bacteriologist who counted the cells in a flowing capillary system. Moldavan pumped cells through a capillary tube focused under a microscope for visualization. The invention of photometry allowed the measurement of differentially-stained cells, and Louis Kamentsky developed the first multiparameter flow cytometer in 1965 to identify and count the cancer cells in cervical tissue specimens.
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Sample Preparation for Mass Cytometry Analysis
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Two-Dimensional Multi-parameter Cytometry Platform for Single-Cell Analysis.

Chengxin Wu1, Xue Men2, Meijun Liu1

  • 1Research Center for Analytical Sciences, Department of Chemistry, College of Sciences, Northeastern University, Shenyang 110819, China.

Analytical Chemistry
|August 23, 2023
PubMed
Summary
This summary is machine-generated.

A novel 2D flow cytometry platform, CytoLM Plus, enables multi-parameter single-cell analysis by combining optical detection with inductively coupled plasma mass spectrometry (ICP-MS). This integrated system achieves high accuracy for detailed cellular analysis.

Area of Science:

  • Analytical Chemistry
  • Biotechnology
  • Single-cell analysis

Background:

  • Traditional flow cytometry offers limited multi-parametric analysis.
  • Integrating optical detection with mass spectrometry presents technical challenges.

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