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The disease burden of respiratory syncytial virus in Infants

Alasdair P S Munro1,2, Federico Martinón-Torres3,4,5, Simon B Drysdale6,7

  • 1NIHR Southampton Clinical Research Facility and Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust.

Current Opinion in Infectious Diseases
|August 23, 2023
PubMed

Insights

Respiratory syncytial virus (RSV) causes significant infant illness globally. New prophylactic treatments, including monoclonal antibodies and maternal immunizations, are expected to reduce this burden on healthcare systems.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Public Health

Background:

  • Respiratory syncytial virus (RSV) is a major cause of infant morbidity and mortality worldwide.
  • Historically, limited therapeutic options have been available for healthy infants to prevent RSV infection.

Conclusions:

  • Emerging long-acting monoclonal antibodies and maternal immunizations offer promising solutions for RSV prevention in infants.
  • These novel therapies are expected to reduce healthcare system strain during winter seasons.
Abstract

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