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Updated: Jul 18, 2025

05:47
Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
277
Knowledge-enhanced Graph Topic Transformer for Explainable Biomedical Text Summarization
IEEE Journal of Biomedical and Health Informatics
|August 23, 2023
Summary
This study introduces DORIS, a novel approach to biomedical text summarization that enhances accuracy and explainability. DORIS integrates domain knowledge and graph topic modeling to generate more coherent and transparent summaries from scientific literature.
Area of Science:
- Biomedical Informatics
- Natural Language Processing
- Artificial Intelligence
Background:
- The rapid growth of biomedical literature necessitates effective automatic summarization.
- Current pre-trained language models (PLMs) for summarization lack domain-specific knowledge, leading to incoherent and incomplete summaries.
- Explainability is critical for trust and understanding in biomedical text summarization.
Purpose of the Study:
- To develop a novel model for explainable biomedical text summarization.
- To improve the accuracy and coherence of summaries generated from biomedical literature.
- To address the limitations of existing PLM-based methods by incorporating domain knowledge.
Main Methods:
- Proposed a domain knowledge-enhanced graph topic transformer (DORIS) model.
- Integrated graph neural topic modeling with domain-specific knowledge from the Unified Medical Language System (UMLS).
- Fine-tuned transformer-based PLMs to enhance summarization capabilities.
Main Results:
- DORIS outperforms existing state-of-the-art PLM-based methods in biomedical extractive summarization.
- The model demonstrates improved accuracy and coherence in generated summaries.
- Graph neural topic modeling provides inherent explainability, clarifying sentence selection processes.
Conclusions:
- DORIS offers a significant advancement in explainable biomedical text summarization.
- Integrating domain knowledge and graph topic modeling enhances summary quality and transparency.
- The model provides a more understandable and reliable approach to summarizing complex biomedical information.
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