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Published on: March 26, 2018
Coronary Embolism After Transcatheter Aortic Valve Replacement-Case Series and Review of Literature
Aviram Akuka1, Uri Landes1, Lisa Manevich1
1Department of Cardiology, Wolfson Medical Center, Holon, Israel; School of Medicine, Tel-Aviv University, Tel Aviv, Israel.
Insights
Coronary embolism after transcatheter aortic valve replacement (TAVR) is underreported. This study suggests TAVR-associated coronary embolism is more common than previously thought, potentially causing myocardial infarction.
Area of Science:
- Cardiology
- Interventional Cardiology
- Vascular Medicine
Background:
- Systemic embolism is a known complication of transcatheter aortic valve replacement (TAVR).
- Cerebral embolism receives significant attention, while coronary embolism is less investigated.
- Coronary embolism post-TAVR can lead to increased morbidity and mortality.
Conclusions:
- Coronary embolism following TAVR may be more prevalent than currently documented.
- Subtle presentations of TAVR-associated coronary embolism can be overlooked.
- Further research is needed to accurately determine the prevalence and clinical impact of TAVR-associated coronary embolism.
Abstract:
Periprocedural systemic embolism is a well-documented complication of transcatheter aortic valve replacement (TAVR). Although the most focus was given to cerebral embolism (which remains unpredictable, difficult to prevent, and a source of increased morbidity and mortality after TAVR), coronary embolism remains less investigated and potentially overlooked. This study provides a case series of 3 patients diagnosed with coronary embolism after TAVR in our institution over a 2-year period (3 of 297 cases, 1%) and a systematic literature review (4 studies; 19 case reports). Overall, coronary embolism associated with TAVR is frequently characterized by proximal vessel occlusion causing ST-elevation myocardial infarction and hemodynamic instability with lower mortality in the acute phase as compared with late coronary embolism. However, it often presents with distal vessel occlusion and minor symptoms that may be overlooked in the periprocedural period. In conclusion, we suggest that TAVR-associated coronary embolism has a much higher prevalence than previously documented. Further studies are warranted to properly assess the prevalence and impact of this phenomenon.
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