Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Mitral Regurgitation III: Medical Management01:25

Mitral Regurgitation III: Medical Management

18
Mitral regurgitation (MR) is characterized by retrograde blood circulation from the left ventricle into the left atrium due to inadequate mitral valve closure. The severity of the condition, symptoms, and underlying cause determine treatment strategies.Monitoring and Pharmacological TreatmentPatients with mild to moderate MR typically do not need immediate intervention but regular monitoring to assess progression and guide treatment. Patients with mild MR should have an echocardiogram every 3-5...
18
Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

13
Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
13
Mitral Regurgitation IV: Nursing Management01:28

Mitral Regurgitation IV: Nursing Management

46
Mitral regurgitation (MR) is a condition where the mitral valve does not close properly, leading to the backward flow of blood from the left ventricle into the left atrium during systole. This condition can arise from various causes, including rheumatic fever, infective endocarditis, or degenerative valve disease. Effective nursing management is crucial to optimizing patient outcomes and involves comprehensive assessment and targeted interventions.Comprehensive Patient AssessmentA detailed...
46
Mitral Stenosis IV: Nursing Management01:27

Mitral Stenosis IV: Nursing Management

14
A comprehensive nursing assessment is essential for patients with valvular heart disease, which involves any dysfunction of the heart valves that could impact blood flow and overall heart function.Subjective Data Collection:Chief Complaint and Present Illness: Start with the patient's primary concerns, focusing on the onset, duration, and progression of cardiac symptoms such as dyspnea, fatigue, chest pain, and palpitations.Past Medical History: Collect detailed information on any previous...
14
Mitral Valve Prolapse II: Assessment and Management01:22

Mitral Valve Prolapse II: Assessment and Management

22
IntroductionA range of clinical features characterizes Mitral Valve Prolapse (MVP), but it is important to note that many individuals with MVP are asymptomatic and may remain so throughout their lives. For those who do exhibit symptoms, the following are the key clinical features:Palpitations: This is a common symptom where individuals feel an irregular or rapid heartbeat. Palpitations in MVP are often due to arrhythmias such as premature ventricular contractions or supraventricular...
22
Heart Failure VI: Adjunct Therapies01:22

Heart Failure VI: Adjunct Therapies

16
Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.
16

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Select Contemporary Statistical Concepts in Heart Failure Clinical Trials: Insights From the Heart Failure Collaboratory.

JACC. Heart failure·2026
Same author

Right Ventricular Metrics as End Points in Clinical Trials: A Review.

JAMA cardiology·2026
Same author

Early effects of SGLT2 inhibitors in acute heart failure: an individual patient-level meta-analysis.

European journal of heart failure·2026
Same author

Real-time cardiac power output index predicts imminent need for extracorporeal membrane oxygenation after heart transplantation.

JHLT open·2026
Same author

Rebuilding U.S. Heart Failure Site-Based Research: A National Expert Authority Blueprint From the Heart Failure Collaboratory.

JACC. Heart failure·2026
Same author

Right Ventricular Function and Echocardiographic Characteristics After Left Atrial to Coronary Sinus Shunting; Insights from ALT-FLOW Early Feasibility Study 3 Year Follow-Up.

Journal of cardiac failure·2026
Same journal

REVEALing New Standards: Low Risk Redefined.

JACC. Heart failure·2026
Same journal

Implantable Cardioverter-Defibrillator Therapy in Contemporary Heart Failure Patients: An Analysis From the EMPEROR-Reduced Trial.

JACC. Heart failure·2026
Same journal

Sodium-Glucose Cotransporter 2 Inhibitor Following Left Ventricular Assist Device Implantation: A Randomized Controlled Trial.

JACC. Heart failure·2026
Same journal

Noninvasive Wearable-Based Algorithm to Predict Worsening Heart Failure by Change in Natriuretic Peptide Levels.

JACC. Heart failure·2026
Same journal

Long-Term HM3 Outcomes: Is Age the Signal or the Surrogate?

JACC. Heart failure·2026
Same journal

Impact of Age on Long-Term Clinical Outcomes Following HeartMate 3 LVAD Implantation: Insights From the MOMENTUM 3 Trial.

JACC. Heart failure·2026
See all related articles

Related Experiment Video

Updated: Jul 18, 2025

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
08:31

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair

Published on: October 16, 2021

3.9K

Mitral Interventions in Heart Failure.

Matthew M Lander1, Michael I Brener2, Kashish Goel3

  • 1Cardiovascular Institute at Allegheny Health Network, Pittsburgh, Pennsylvania, USA.

JACC. Heart Failure
|August 23, 2023
PubMed
Summary
This summary is machine-generated.

Secondary mitral regurgitation (SMR) in heart failure with reduced ejection fraction worsens outcomes. Transcatheter edge-to-edge repair offers a promising percutaneous intervention, expanding treatment options for these patients.

Keywords:
MitraClipguideline-directed medical therapymitral transcatheter edge-to-edge repairsecondary mitral regurgitationtranscatheter mitral valve replacement

More Related Videos

Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction
09:20

Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction

Published on: February 13, 2021

6.5K
Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
08:12

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels

Published on: May 26, 2023

1.7K

Related Experiment Videos

Last Updated: Jul 18, 2025

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
08:31

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair

Published on: October 16, 2021

3.9K
Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction
09:20

Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction

Published on: February 13, 2021

6.5K
Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
08:12

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels

Published on: May 26, 2023

1.7K

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Heart Failure Management

Background:

  • Secondary mitral regurgitation (SMR) in heart failure with reduced ejection fraction (HFrEF) is linked to adverse patient outcomes and diminished quality of life.
  • Guideline-directed medical therapy remains the primary treatment approach for SMR.

Purpose of the Study:

  • To review the evolving role of transcatheter edge-to-edge repair (TEER) for SMR in HFrEF patients.
  • To identify patient subgroups likely to benefit from percutaneous interventions.
  • To explore the potential of TEER in previously unstudied populations.

Main Methods:

  • Analysis of landmark clinical trials focusing on TEER for SMR.
  • Emphasis on a multidisciplinary approach to patient selection and management.
  • Evaluation of emerging transcatheter devices and ongoing clinical trials.

Main Results:

  • Landmark trials have refined the understanding of patient selection for TEER in SMR.
  • TEER success has prompted its investigation in advanced heart failure populations, including cardiogenic shock.
  • A growing pipeline of transcatheter devices is expanding therapeutic options.

Conclusions:

  • TEER is an increasingly important percutaneous intervention for symptomatic SMR in HFrEF.
  • A multidisciplinary strategy is crucial for optimizing outcomes with TEER.
  • Future transcatheter innovations promise further advancements in managing HFrEF with SMR.