Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Bereavement and catecholamines.

S C Jacobs, J W Mason, T R Kosten

    Journal of Psychosomatic Research
    |January 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Comparison of PR, QRS, and QT interval measurements by seven ECG interpretation programs.

    Journal of electrocardiology·2020
    Same author

    Tobacco.

    The American journal of dental science·2019
    Same author

    Late sodium current block for drug-induced long QT syndrome: Results from a prospective clinical trial.

    Clinical pharmacology and therapeutics·2015
    Same author

    Lacosamide cardiac safety: clinical trials in patients with partial-onset seizures.

    Acta neurologica Scandinavica·2015
    Same author

    Differentiating drug-induced multichannel block on the electrocardiogram: randomized study of dofetilide, quinidine, ranolazine, and verapamil.

    Clinical pharmacology and therapeutics·2014
    Same author

    Management of headaches.

    Highlights of ophthalmology·2014
    Same journal

    Association of kynurenine metabolites with cognitive and psychological symptoms in post COVID-19 condition: A case-control study.

    Journal of psychosomatic research·2026
    Same journal

    Applying the functional somatic disorder classification to somatic symptom disorder: Findings from the SOMA.SSD study.

    Journal of psychosomatic research·2026
    Same journal

    Psychological and medical outcomes of post-COVID-19 patients: A longitudinal study.

    Journal of psychosomatic research·2026
    Same journal

    Beyond general depression: Premenstrual interpersonal anger as a unique pathway to suicidal ideation in adolescent females with ADHD.

    Journal of psychosomatic research·2026
    Same journal

    Function-based reorganization of general hospital psychiatry in Japan: A perspective.

    Journal of psychosomatic research·2026
    Same journal

    Metabolic and psychiatric changes after laparoscopic sleeve gastrectomy in patients with mood disorders and metabolic syndrome.

    Journal of psychosomatic research·2026
    See all related articles

    Urinary catecholamine output, specifically norepinephrine and epinephrine, was higher in acutely bereaved individuals. Age was associated with increased output in older bereaved subjects, indicating slower stress adaptation.

    Area of Science:

    • Psychoneuroendocrinology
    • Stress Physiology

    Background:

    • Bereavement and spousal loss are significant stressors.
    • The sympathetic-adrenal medullary (SAM) system's response to stress is crucial in human health.

    Purpose of the Study:

    • To investigate urinary catecholamine levels in individuals experiencing acute bereavement or threat of spousal loss.
    • To examine the relationship between psychological distress and catecholamine output during bereavement.
    • To assess the impact of age on SAM system response to bereavement.

    Main Methods:

    • Measured 24-hour urinary output of norepinephrine and epinephrine in 59 middle-aged and elderly subjects.
    • Compared output in acutely bereaved (n=39) and threatened-loss (n=20) groups against literature norms.
    • Assessed psychological distress and depression scores.

    Related Experiment Videos

    Main Results:

    • Urinary norepinephrine and epinephrine were elevated in acutely bereaved individuals compared to controls.
    • No significant differences in catecholamine output were found between the acutely bereaved and threatened-loss groups.
    • No association was observed between psychological distress or depression scores and catecholamine levels.
    • Increasing age correlated with higher urinary catecholamine output in the acutely bereaved group.

    Conclusions:

    • Acute bereavement leads to elevated urinary catecholamine output.
    • The SAM system's adaptation to stress may be slower in older individuals.
    • Psychological distress measures did not correlate with catecholamine levels in this cohort.