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Published on: February 15, 2022
Netarsudil in the management of refractory pediatric glaucoma
Bo Wang1, Caroline M Zimmermann2, Courtney L Kraus3
1Wilmer Eye Institute, Johns Hopkins Medicine, Baltimore, Maryland; Duke University Hospital, Durham, North Carolina.
Insights
Netarsudil offers limited IOP lowering in pediatric glaucoma patients with refractory cases. Close monitoring for corneal issues is crucial, particularly in those with prior corneal disease.
Area of Science:
- Ophthalmology
- Pediatric Ophthalmology
- Glaucoma Research
Background:
- Pediatric glaucoma presents unique management challenges.
- Refractory pediatric glaucoma often requires advanced treatment strategies.
- Netarsudil offers a novel mechanism for intraocular pressure (IOP) reduction.
Abstract:
We performed a retrospective review of patients with refractory pediatric glaucoma who were started on netarsudil at the Wilmer Eye Institute. We found minimally sustained IOP lowering over a 6-month period in 29 eyes of 23 patients. Our results suggest that although netarsudil is an alternative medication in the management of pediatric glaucoma, its efficacy may be limited in refractory pediatric glaucoma patients. In addition, careful cornea examination is required to evaluate for signs of corneal decompensation, especially in patient with preexisting cornea disease.
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