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Tropical spastic paraparesis
1Department of Neurology, Methodist Neurological Institute, Weill Cornell Medical College, Houston Methodist Hospital, Houston, TX, United States.
Handbook of Clinical Neurology
|August 24, 2023
Summary
Spinal cord disorders in the tropics are diverse, including infections, nutritional deficiencies, and toxins like HTLV-1 causing tropical spastic paraparesis (TSP). Modern imaging aids diagnosis and treatment of these disabling conditions.
Area of Science:
- Neurology
- Tropical Medicine
- Infectious Diseases
Background:
- Spinal cord disorders in tropical regions present unique challenges, with infectious and nutritional etiologies being more prevalent than in temperate zones.
- Common causes include Pott's disease, brucellosis, parasitic infections (schistosomiasis, neurocysticercosis), and malnutrition-related myeloneuropathies.
- Human T-lymphotropic virus type 1 (HTLV-1) is a significant cause of tropical spastic paraparesis/paraplegia (TSP).
Conclusions:
- Spinal cord disorders in the tropics encompass a broad spectrum of etiologies, with infectious and nutritional factors playing a prominent role.
- Effective diagnosis and treatment of conditions like TSP are crucial for reducing mortality and disability.
- Advancements in medical imaging are transforming the approach to managing these neurological conditions in tropical healthcare settings.
Keywords:
Acute tropical myeloneuropathyBeriberiHTLV-1Retroviral myelopathiesStrachan syndromeToxic neuropathyTransverse myelitisTropical spastic paraparesisVitamin deficienciesMore Related Videos
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