Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Parkinson's Disease: Overview01:15

Parkinson's Disease: Overview

596
Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
596
Seizures: Classification01:13

Seizures: Classification

411
Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
411
Restless Leg Syndrome and Night Terrors01:27

Restless Leg Syndrome and Night Terrors

203
Restless Leg Syndrome (RLS), also known as Willis-Ekbom disease, is a neurological disorder characterized by an uncontrollable urge to move the legs due to uncomfortable sensations. These sensations typically occur during periods of rest or inactivity, particularly when lying down or sitting, and can severely disrupt sleep.
The exact cause of RLS is not fully understood, but it is believed to involve dopamine, a neurotransmitter that helps regulate muscle movement. Imbalances in dopamine levels...
203
Generalized Anxiety Disorder01:30

Generalized Anxiety Disorder

165
Generalized Anxiety Disorder (GAD) is a chronic condition characterized by excessive and uncontrollable worry that persists for at least six months, significantly interfering with daily functioning. Unlike situational anxiety, which arises in response to specific stressors, GAD often occurs without a clear cause. Individuals may experience disproportionate worry about work, health, or relationships. For instance, a person might continuously fear poor health despite normal medical evaluations or...
165
Parkinson's Disease: Treatment01:24

Parkinson's Disease: Treatment

297
Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
297
Physical Pendulum01:06

Physical Pendulum

1.8K
When a rigid body is hanging freely from a fixed pivot point and is displaced, it oscillates similar to a simple pendulum and is known as a physical pendulum. The period and angular frequency of a physical pendulum are obtained by using the small-angle approximation and drawing parallels with a spring-mass system. The small-angle approximation (sinθ=θ) is valid up to about 14°.
When dealing with complicated systems, the mass moment of inertia is an important parameter, as it...
1.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Baseline Infection Burden and Cognitive Function in Elders with Essential Tremor.

Tremor and other hyperkinetic movements (New York, N.Y.)·2021
Same author

The Essential Tremors: Evolving Concepts of a Family of Diseases.

Frontiers in neurology·2021
Same author

The Neurological Study Unit: "A Combined Attack on a Single Problem from Many Angles".

Canadian bulletin of medical history = Bulletin canadien d'histoire de la medecine·2021
Same author

The Progression of Essential Tremors: Illustrative Videos.

Tremor and other hyperkinetic movements (New York, N.Y.)·2021
Same author

Essential Tremor versus "ET-plus": A Detailed Postmortem Study of Cerebellar Pathology.

Cerebellum (London, England)·2021
Same author

Demoralization and Quality of Life of Patients with Parkinson Disease.

Psychotherapy and psychosomatics·2021
Same journal

Preface.

Handbook of clinical neurology·2026
Same journal

Foreword.

Handbook of clinical neurology·2026
Same journal

Fundus autofluorescence imaging.

Handbook of clinical neurology·2026
Same journal

The electroretinogram as a means to study the physiology of the retina.

Handbook of clinical neurology·2026
Same journal

Adaptive optics scanning light ophthalmoscopy.

Handbook of clinical neurology·2026
Same journal

Modeling the human retina in a dish: Advances and future directions.

Handbook of clinical neurology·2026
See all related articles

Related Experiment Video

Updated: Jul 18, 2025

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor
05:54

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor

Published on: December 13, 2017

14.0K

Essential tremor.

Elan D Louis1

  • 1Department of Neurology, University of Texas Southwestern Medical Center, Dallas, TX, United States.

Handbook of Clinical Neurology
|August 24, 2023
PubMed
Summary
This summary is machine-generated.

Essential tremor (ET) is a progressive neurologic disorder characterized by kinetic tremor. Research suggests ET may be a family of disorders with cerebellar degeneration.

Keywords:
Action tremorEssential tremorKinetic tremorNeurodegenerationProgressives

More Related Videos

Extraction of the EPP Component from the Surface EMG
07:16

Extraction of the EPP Component from the Surface EMG

Published on: December 16, 2009

12.6K
A Standardized Method for Measurement of Elbow Kinesthesia
07:56

A Standardized Method for Measurement of Elbow Kinesthesia

Published on: October 10, 2020

7.1K

Related Experiment Videos

Last Updated: Jul 18, 2025

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor
05:54

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor

Published on: December 13, 2017

14.0K
Extraction of the EPP Component from the Surface EMG
07:16

Extraction of the EPP Component from the Surface EMG

Published on: December 16, 2009

12.6K
A Standardized Method for Measurement of Elbow Kinesthesia
07:56

A Standardized Method for Measurement of Elbow Kinesthesia

Published on: October 10, 2020

7.1K

Area of Science:

  • Neurology
  • Neuroscience
  • Pathology

Background:

  • Essential tremor (ET) is a chronic, progressive neurologic disease.
  • Characterized by a 4-12Hz kinetic tremor during voluntary movements.
  • May present with postural, rest, or intention tremors, motor, and nonmotor features.

Conclusions:

  • Essential tremor is likely a degenerative disorder with a primary role for the cerebellum.
  • Further research may redefine ET as "the essential tremors" due to its heterogeneity.
  • Understanding ET's degenerative nature is crucial for diagnosis and treatment.