Related Experiment Video
Updated: Jul 18, 2025
06:05
The Participant-Reported Implementation Update and Score PRIUS: A Novel Method for Capturing Implementation-Related Data Over Time
Published on: February 19, 2021
1.3K
Understanding how PrEP is made successful: Implementation science needs an evidence-making approach.
Anthony K J Smith1, Kari Lancaster1, Tim Rhodes1,2
1Centre for Social Research in Health, UNSW Sydney, Sydney, Australia.
Global Public Health
|August 25, 2023
Summary
Next-generation HIV pre-exposure prophylaxis (PrEP) requires understanding implementation science. An
Area of Science:
- Implementation Science
- Public Health
- HIV Prevention
Background:
- Oral pre-exposure prophylaxis (PrEP) for HIV has been available for a decade.
- The next generation of PrEP, including long-acting formulations, is anticipated.
- Uneven international PrEP implementation highlights the need for contextual understanding.
Purpose of the Study:
- To explore the evolution of PrEP and advocate for an 'evidence-making' approach.
- To understand how implementation contexts shape PrEP's translation and effects.
- To recognize that interventions and their contexts co-evolve.
Main Methods:
- Literature review and conceptual analysis.
- Exploration of implementation science principles.
- Framing implementation as 'evidence-making events'.
Main Results:
- PrEP implementation is shaped by local contexts and health systems.
- Interventions and implementation contexts are co-constituted and evolve together.
- Challenging universal assumptions about intervention effects is crucial.
Conclusions:
- An 'evidence-making' approach is vital for next-generation PrEP.
- Implementation science must view processes as co-evolving events.
- Harnessing localized possibilities will optimize PrEP's future impact.
More Related Videos
05:47Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
277
10:26Problem-Solving Before Instruction PS-I: A Protocol for Assessment and Intervention in Students with Different Abilities
Published on: September 11, 2021
4.0K
Related Concept Videos
01:26Introduction to Epidemiology
773
Epidemiology, known as the cornerstone of public health, involves studying the distribution and determinants of health-related events in defined populations and applying these insights to control health issues. This is essential for understanding how diseases spread, identifying populations at greater risk, and implementing measures to control or prevent outbreaks. Epidemiology addresses not only infectious diseases but also non-communicable conditions like cancer and cardiovascular disease,...
773
01:13Psychology as a Science
750
Psychology, as a scientific discipline, aims to understand the mind and behavior through rigorous and systematic methods. The foundation of psychological research is evidence-based, relying heavily on the scientific method to derive and validate knowledge. This structured approach ensures that findings are reliable, valid, and applicable to broader contexts.
The scientific method in psychology involves six critical steps: making observations, formulating hypotheses, conducting tests, analyzing...
The scientific method in psychology involves six critical steps: making observations, formulating hypotheses, conducting tests, analyzing...
750
01:21Methods of Documentation III: PIE
1.4K
Problem-intervention-evaluation (PIE) is a systematic approach to documentation used in healthcare settings for clinical decision-making and patient care planning. It is a structured approach to organizing patient data based on problems, interventions, and evaluations. Here's a breakdown of its key features and considerations:
1.4K
01:12What is an Experiment?
11.7K
An experiment is a planned activity carried out under controlled conditions. The purpose of an experiment is to investigate the relationship between two variables. When one variable causes change in another, we call the first variable the explanatory or independent variable. The affected variable is called the response or dependent variable. In a randomized experiment, the researcher manipulates values of the explanatory variable and measures the resulting changes in the response variable. The...
11.7K
01:25Strategies for Assessing and Addressing Confounding
119
Confounding is a critical issue in epidemiological studies, often leading to misleading conclusions about associations between exposures and outcomes. It occurs when the relationship between the exposure and the outcome is mixed with the effects of other factors that influence the outcome. Given that, addressing confounding is of high importance for drawing accurate inferences in research.
Confounding can be addressed at both the design phase of a study and through analytical methods after data...
Confounding can be addressed at both the design phase of a study and through analytical methods after data...
119
01:20Study Designs in Epidemiology
266
Epidemiological study designs are fundamental tools for investigating the distribution, determinants, and control of health conditions in populations. They help researchers understand the relationships between exposures and outcomes, and they broadly fall into two categories: "observational" and "experimental" studies.
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and...
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and...
266