Related Experiment Video
Updated: Jul 18, 2025
05:53
Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
Published on: June 21, 2018
10.2K
Special Issue: "Genetic Counseling and Genetic Testing in Precision Medicine".
Erin Turbitt1, Chris Jacobs1,2, Alison McEwen1
1Discipline of Genetic Counselling, University of Technology Sydney, Ultimo, NSW 2007, Australia.
Journal of Personalized Medicine
|August 25, 2023
Summary
Genomic technologies are advancing healthcare, leading to better health outcomes. These innovations in medical genomics improve patient well-being through personalized medicine.
Area of Science:
- Genomics and Bioinformatics
- Translational Medicine
- Health Informatics
Background:
- Genomic technologies have revolutionized medical research and clinical practice.
- Advancements enable deeper understanding of genetic basis of diseases.
- Integration of genomic data into healthcare systems is crucial.
Discussion:
- The impact of genomic technologies on public health is significant and growing.
- Ethical considerations and data privacy are paramount in genomic applications.
- Interdisciplinary collaboration is key to harnessing genomic potential.
Key Insights:
- Genomic innovations drive personalized medicine and targeted therapies.
- Improved diagnostics and risk prediction are direct benefits.
- Genomic data aids in understanding disease mechanisms and progression.
Outlook:
- Future applications include advanced gene editing and synthetic biology.
- Wider accessibility of genomic sequencing will democratize healthcare.
- Continued research will uncover novel therapeutic targets and strategies.
Related Concept Videos
01:28Human Genetics
611
Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
The complex relationship between genetics and psychology is observable through common biological components such...
611
02:50Combination Therapies and Personalized Medicine
4.9K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
4.9K
00:49What is Genetic Engineering?
74.3K
Overview
74.3K
01:23Behavioral Genetics and Its Designs
407
Behavior genetics explores how genetic inheritance influences human behavior. It focuses on how genes, passed from parents to offspring, contribute to the development of behavioral traits and tendencies. This branch of genetics seeks to understand the complex interplay between inherited genetic factors and environmental influences in shaping our behaviors.
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...
407
01:11Genome-wide Association Studies-GWAS
13.6K
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
GWAS does not require the identification of the target gene involved in...
13.6K
02:30Genomic Imprinting and Inheritance
34.7K
Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
34.7K