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Related Concept Videos

Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

8
Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
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Endocarditis I: Introduction01:25

Endocarditis I: Introduction

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Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
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Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

23
Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
23
Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

25
Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
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Related Experiment Video

Updated: Jul 18, 2025

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
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Surgery for Infective Endocarditis after Primary Transcatheter Aortic-Valve Replacement-A Retrospective Single-Center

Romina Maria Rösch1,2, Lena Brendel1,2, Katja Buschmann2

  • 1Department of Thoracic Surgery, Thoraxklinik Heidelberg, Heidelberg University Hospital, 69126 Heidelberg, Germany.

Journal of Clinical Medicine
|August 26, 2023
PubMed
Summary

Transcatheter aortic-valve replacement (TAVR) is rising, increasing prosthetic-valve endocarditis. Surgical intervention for TAVR infective endocarditis offers good outcomes and should be considered for high-risk patients.

Keywords:
heart-valve pathologiesheart-valve prosthesisheart-valve treatmentinfective endocarditisprosthetic-valve endocarditistranscatheter aortic-valve implantationvalve repair

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Area of Science:

  • Cardiology
  • Cardiac Surgery
  • Infectious Diseases

Background:

  • Transcatheter aortic-valve replacement (TAVR) is a growing treatment for aortic stenosis.
  • The increasing use of TAVR leads to a rise in patients with aortic-valve prostheses.
  • Consequently, prosthetic-valve endocarditis incidence is escalating.

Purpose of the Study:

  • To evaluate surgical outcomes for patients with prosthetic-valve endocarditis following TAVR.
  • To assess the feasibility and efficacy of surgical intervention in this patient cohort.

Main Methods:

  • Retrospective analysis of ten patients who underwent surgery for prosthetic-valve endocarditis post-TAVR between March 2016 and July 2019.
  • Data collected included patient demographics, microbiological findings, prosthesis sizes, and clinical outcomes.

Main Results:

  • Infective endocarditis occurred 17 ± 16 months post-TAVR in patients with a mean age of 79 years.
  • Enterococcus faecalis was identified in 60% of positive blood cultures.
  • One in-hospital mortality occurred; all other patients survived with a mean follow-up of 9 months.

Conclusions:

  • Prosthetic-valve endocarditis post-TAVR is an increasing concern, particularly in high-risk individuals.
  • Surgical treatment for TAVR infective endocarditis can yield favorable results.
  • Surgical intervention should remain a viable option for TAVR patients diagnosed with infective endocarditis.