Development of a Website for a Living Network Meta-analysis of Atopic Dermatitis Treatments Using a User-Centered...

Area of Science:

• Dermatology
• Clinical Immunology
• Health Informatics

Background:

• Systemic immunological treatments for atopic dermatitis (AD) are rapidly expanding.
• A need exists for clear, comparative efficacy and safety data for patients and clinicians.
• Network meta-analysis (NMA) offers comparative insights but results are often complex.

Purpose of the Study:

• To develop a user-friendly website presenting living systematic review and NMA results for AD treatments.
• To facilitate shared decision-making between patients and clinicians regarding treatment options.

Main Methods:

• A user-centered design framework guided the study, incorporating feedback from patients, caregivers, and clinicians.
• Iterative development involved questionnaires and workshops to refine the website interface.
• Usability testing was conducted with a caregiver of an eczema patient.

Main Results:

• Patients and caregivers prioritized information on new treatments and avoiding side effects.
• Clinicians identified a lack of evidence-based treatment comparisons as a care barrier.
• Users found visualizations of NMA results valuable for comparing treatments and simplifying the interface.

Conclusions:

• A user-centered website, eczematherapies.com, was developed to present complex NMA data.
• Visualizations enable accessible comparison of AD treatments for shared decision-making.
• The website addresses the need for understandable comparative treatment information.